Sökning: "folate"

Visar resultat 36 - 40 av 67 avhandlingar innehållade ordet folate.

1. 36. Diet and gastrointestinal cancer : one-carbon metabolism and other aspects

   Författare :Susanna C Larsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Diet has been hypothesized to play a major role in the etiology of gastrointestinal cancer, but the specific dietary factors involved remain unclear. The aims of this thesis were: to examine the associations of dietary magnesium and vitamin B6 intakes with risk of colorectal cancer in the Swedish Mammography Cohort (SMC); to evaluate the relation between folate intake and risk of pancreatic cancer in the SMC and the Cohort of Swedish Men (COSM); to use metaanalysis to summarize the evidence from published studies of the associations of folate intake and polymorphisms in the gene encoding 5,10-methylenetetrahydrofolate reductase (MTHFR C677T and A1298C), a central enzyme in one-carbon metabolism, with risk of esophageal, gastric, pancreatic, and colorectal cancer; and to perform a meta-analysis of epidemiologic studies of the relationship between processed meat consumption and risk of gastric cancer. LÄS MER

3. 37. Aspects on clinical diagnosis of dementia, with focus on biological markers

   Författare :Katarina Nägga; Lars-Olof Wahlund; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The clinical dementia diagnosis has become more complex with increasing knowledge of the heterogeneity of the disorder and its different aetiological aspects. A clinical dementia population and a control group were investigated with the following aims: I. LÄS MER

4. 38. On HIV in the elderly and vitamin B metabolism in HIV infection

   Författare :Erika Tyrberg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; elderly; drug levels; potential drug-drug interactions; inflammation; immune activation; antiretroviral therapy; homocysteine; neurofilament light protein;

   Sammanfattning : The evolution of the human deficiency virus (HIV) field is unparalleled in the history of infectious diseases. From the first cases in the beginning of the 1980s, when an HIV diagnosis was a death sentence, through the discovery of the first effective medicines, up till today when people living with HIV (PLHIV) with access to antiretroviral therapy (ART) can lead a near normal life. LÄS MER

5. 39. Drug discovery against leishmaniasis : Bio- and chemoinformatic guided strategies for target evaluation and hit identification

   Författare :Elisabet Vikeved; UCM Alsmark; Christian Sköld; David Horn; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leishmaniasis; Drug discovery; Lateral gene transfer; Comparative genomics; Virtual screening; Target fishing; Marine natural products;

   Sammanfattning : Leishmaniasis is a neglected tropical disease mainly affecting poor people in developing countries. It is caused by infections of flagellated protozoa belonging to genus Leishmania. The few available drugs are associated with problems such as low effectiveness, severe side effects and resistance development. LÄS MER

7. 40. Urologic and metabolic consequences of continent urostomy (Kock reservoir) in children and adolescents

   Författare :Gamal Abd El-Gawad; Göteborgs universitet; []
   Nyckelord :Urinary diversion; Continent ileal urostomy; Kock pouch; Complication; Enterocystography; Enterocystometry; Urography; B12; Folic acid; MMA; Quality of life.;

   Sammanfattning : During the last decades, urinary diversion using an intestinal segment has been commonly used in children and adolescents. Kock pouch is a feasible alternative for the children in need of a continent diversion where other alternatives such as Mitrofanoff are excluded for various reasons. LÄS MER