Sökning: "enzyme technology"

Visar resultat 21 - 25 av 482 avhandlingar innehållade orden enzyme technology.

  1. 21. Catalysis and Site-Specific Modification of Glutathione Transferases Enabled by Rational Design

    Författare :Sofia Håkansson Hederos; Lars Baltzer; Kerstin Broo; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Catalysis; Glutathione Transferases; Rational design; Protein design; Site-specific modification; thiolester hydrolysis; Enzyme engineering; Enzymteknik;

    Sammanfattning : This thesis describes the rational design of a novel enzyme, a thiolester hydrolase, derived from human glutathione transferase (GST) A1-1 by the introduction of a single histidine residue. The first section of the thesis describes the design and the determination of the reaction mechanism. LÄS MER

  3. 22. Engineered Alcohol Dehydrogenases for Stereoselective Chemical Transformations

    Författare :Thilak Reddy Enugala; Mikael Widersten; Manfred T. Reetz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; alcohol dehydrogenase-A; biocatalysts; protein engineering; enzyme kinetics; sec-alcohols; ketones; stereoselectivity; regioselectivity; substrate selectivity and promiscuity.; Biokemi; Biochemistry;

    Sammanfattning : Enzymes are biomolecules built from amino acids and catalyze the chemical transformations in a cell. Enzymes are by nature stereoselective, biodegradable, environmentally friendly, and can perform catalysis in aqueous solutions and at ambient temperatures. LÄS MER

  4. 23. Advancement of sensor technology for monitoring and control of upstream bioprocesses

    Författare :Judit Randek; Carl-Fredrik Mandenius; Gerald Striedner; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : In bioprocesses, the upstream process part with cultivation and harvesting steps has decisive influence on the final process outcome, including the quality of the product, the productivity and the yield. To ensure stable product quality of biopharmaceuticals, the U.S. LÄS MER

  5. 24. Immobilization of feruloyl esterases in mesoporous silica

    Författare :Christian Thörn; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Mesoporous materials; Feruloyl esterases; Protein modeling; Biocatalysis; QCM-D; Hydroxycinnamic acids; Enzyme immobilization; Silica;

    Sammanfattning : Feruloyl esterases are a class of enzymes that can be used as biocatalysts for the modification of bioactive hydroxycinnamic acids. In industry, enzyme immobilization is often necessary to stabilize the enzymes and to allow their reuse. LÄS MER

  7. 25. Biobased Adipic Acid - Challenges in Establishing a Cell Factory

    Författare :Emma Skoog; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; 2-hexenedioic acid; enzyme engineering; 6-aminohex-2-enoic acid; S. cerevisiae; adipic acid pathway via lysine; cell factory; C. viswanathii; lignocellulose; biorefinery; tolerance; in silico docking; adipic acid;

    Sammanfattning : Growing concern regarding climate change calls for sustainable solutions to significantly reduce our dependency on non-renewable fossil-based raw materials. One potential solution is the development of biorefineries where biobased, renewable raw materials are converted into valuable products via enzymatic, chemical or microbial conversion. LÄS MER