Sökning: "sec-alcohols"

Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet sec-alcohols.

  1. 1. Engineered Alcohol Dehydrogenases for Stereoselective Chemical Transformations

    Författare :Thilak Reddy Enugala; Mikael Widersten; Manfred T. Reetz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; alcohol dehydrogenase-A; biocatalysts; protein engineering; enzyme kinetics; sec-alcohols; ketones; stereoselectivity; regioselectivity; substrate selectivity and promiscuity.; Biokemi; Biochemistry;

    Sammanfattning : Enzymes are biomolecules built from amino acids and catalyze the chemical transformations in a cell. Enzymes are by nature stereoselective, biodegradable, environmentally friendly, and can perform catalysis in aqueous solutions and at ambient temperatures. LÄS MER

  3. 2. Understanding and engineering the enantioselectivity of candida antarctica lipase b towards sec-alcohols

    Författare :Didier Rotticci; KTH; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  4. 3. Studies on Metalloenzymatic Dynamic Kinetic Resolutions and Iron-Catalyzed Reactions of Allenes

    Författare :Karl P. J. Gustafson; Jan-Erling Bäckvall; Johannes de Vries; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Racemization; Dynamic Kinetic Resolution; Enzyme Catalysis; XAS; Asymmetric Synthesis; organisk kemi; Organic Chemistry;

    Sammanfattning : The main focus of this thesis lies in the development of new transition metal-catalyzed chemoenzymatic dynamic kinetic resolutions (DKR) of both alcohols and amines. The first part of the thesis deals with the development of new heterogeneous systems for the DKR of amines. LÄS MER

  5. 4. Transition metal-catalyzed hydrogen transfer processes

    Författare :Oscar Verho; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The first part describes the synthesis of new analogues of Bäckvall’s catalyst with varying electronic properties and their application in the racemization of sec-alcohols. The racemization involves two key steps: (i) β-hydride elimination (dehydrogenation of the alcohol) and (ii) hydride re-addition to the intermediate ketone. LÄS MER

  7. 5. Iron-Catalyzed Reactions and X-Ray Absorption Spectroscopic Studies of Palladium- and Ruthenium-Catalyzed Reactions

    Författare :Arnar Guðmundsson; Jan-Erling Bäckvall; Hans-Joachim Knölker; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Iron; XAS; Cycloisomerization; DKR; Oxidation; organisk kemi; Organic Chemistry;

    Sammanfattning : The focus of this thesis is twofold: The first is on the application of iron catalysis for organic transformations. The second is on the use of in situ X-ray absorption spectroscopy (XAS) to investigate the mechanisms of a heterogeneous palladium-catalyzed reaction and a homogeneous ruthenium-catalyzed reaction. LÄS MER