Sökning: "Manfred T. Reetz"

Hittade 3 avhandlingar innehållade orden Manfred T. Reetz.

  1. 1. Ruthenium-catalyzed redox reactions and lipase-catalyzed asymmetric transformations of alcohols

    Författare :Michaela Edin; Jan-E. Bäckvall; Manfred T. Reetz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ruthenium; lipase; catalysis; alcohols; diols; Chemistry; Kemi;

    Sammanfattning : The major part of this thesis describes the synthesis of enantiopure alcohols and diols by combining ruthenium-catalyzed redox reactions that lead to racemization or epimerization and lipase-catalyzed asymmetric trans-formations in one-pot.A mechanistic study of the unexpected facile formation of meso-diacetate products found in enzyme-catalyzed acetylations of alkanediols with Candida antarctica lipase B (CALB) was first performed. LÄS MER

  3. 2. Enantioselective biotransformations using engineered lipases from Candida antarctica

    Författare :Karin Engström; Jan-E. Bäckvall; Manfred T. Reetz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein engineering; directed evolution; kinetic resolution; dynamic kinetic resolution; biotransformation; lipase; organisk kemi; Organic Chemistry;

    Sammanfattning : Enzymes are attractive catalysts in organic synthesis since they are efficient, selective and environmentally friendly. A large number of enzyme-catalyzed transformations have been described in the literature. LÄS MER

  4. 3. Engineered Alcohol Dehydrogenases for Stereoselective Chemical Transformations

    Författare :Thilak Reddy Enugala; Mikael Widersten; Manfred T. Reetz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; alcohol dehydrogenase-A; biocatalysts; protein engineering; enzyme kinetics; sec-alcohols; ketones; stereoselectivity; regioselectivity; substrate selectivity and promiscuity.; Biokemi; Biochemistry;

    Sammanfattning : Enzymes are biomolecules built from amino acids and catalyze the chemical transformations in a cell. Enzymes are by nature stereoselective, biodegradable, environmentally friendly, and can perform catalysis in aqueous solutions and at ambient temperatures. LÄS MER