Sökning: "engraftment"

Visar resultat 6 - 10 av 79 avhandlingar innehållade ordet engraftment.

  1. 6. The Microvasculature of Endogenous and Transplanted Pancreatic Islets : Blood Perfusion, Oxygenation and Islet Endocrine Function

    Författare :Richard Olsson; Per-Ola Carlsson; Leif Jansson; Arne Andersson; Thomas Linn; Uppsala universitet; []
    Nyckelord :Cell biology; diabetes mellitus; pancreatic islets; islet transplantation; vascular engraftment; islet microcirculation; oxygenation; blood flow; protein biosynthesis; Cellbiologi;

    Sammanfattning : Type 1 diabetes mellitus affects millions of people worldwide. Islet transplantation is a minimal invasive surgical procedure that restores euglycemia and halts the progression of diabetic complications. However, despite transplantation of islets from multiple donors most patients reverse to hyperglycemia within five years. LÄS MER

  3. 7. Neural stem cell engraftment : functional interactions, brain repair and gap junctions

    Författare :Johan Jäderstad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neural stem cell (NSC) engraftment therapies show increasing promise as potential cures for several of the diseases of the central nervous system. Traditionally, functional improvements after NSC engraftment have been attributed to replacement of lost neurons and astrocytes, remyelination and support of adjacent cells at risk. LÄS MER

  4. 8. Experimental models with specific approaches to augment human fetal liver cell engraftment

    Författare :Pradeep B Patil; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transplantation; Cell therapy; Animal models;

    Sammanfattning : Experimental models with specific approaches to augment human fetal liver cell engraftment Pradeep Patil Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg Background: Liver disease is a common cause of morbidity and mortality worldwide. Orthotopic liver transplantation has so far been the only available therapy for patients with end-stage liver failure. LÄS MER

  5. 9. Engraftment and tolerance induction in cellular therapy : focus on mesenchymal stromal cells

    Författare :Karin Ljung; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Different cell types have been employed in the search for a cellular therapy that is applicable for the treatment of heart failure. Remuscularization strategies using stem-cell-derived cardiomyocytes have been prone to arrhythmias. LÄS MER

  7. 10. Molecular monitoring of engraftment and leukemia relapse after allogeneic hematopoietic stem cell transplantation

    Författare :Jonas Mattsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Relapse of the underlying disease, graft-versus-host disease (GVHD) and infections are the main complications after allogeneic hematopoietic stem cell transplantation (HSCT). A lower tumor burden increases the likelihood of cure after both chemotherapy and HSCT. LÄS MER