Sökning: "ebola"

Visar resultat 6 - 10 av 11 avhandlingar innehållade ordet ebola.

  1. 6. Characterizing important flavivirus-host interactions : Replication, assembly, restriction factors and vaccine development

    Författare :Pham Tue Hung Tran; Magnus Johansson; Wessam Melik; Naveed Asghar; Sören Andersson; Laurent Chatel-Chaix; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Flaviviruses; virus-host cell interaction; lunapark; ESCRT; ALIX; CHMP4A; ISG15; TRIMs; replicon virus-like particles; vaccine;

    Sammanfattning : The genus Flavivirus (family Flaviviridae) consists of important zoonotic viruses that cause morbidity and mortality worldwide. These viruses are enveloped and have a positive-sense single-stranded RNA genome encoding a polyprotein. LÄS MER

  3. 7. Exploring the Molecular Behavior of Carbohydrates by NMR Spectroscopy : Shapes, motions and interactions

    Författare :Olof Engström; Göran Widmalm; Anthony S. Serianni; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; NMR relaxation; DNMR; CORCEMA-ST; carbohydrates; caffeine; O-antigen; glycofullerenes; organisk kemi; Organic Chemistry;

    Sammanfattning : Carbohydrates are essential biomolecules that decorate cell membranes and proteins in organisms. They are important both as structural elements and as identification markers. Many biological and pathogenic processes rely on the identification of carbohydrates by proteins, thereby making them attractive as molecular blueprints for drugs. LÄS MER

  4. 8. Cell and organoid models to develop new antivirals and diagnostic methods for emerging viruses

    Författare :Aleksandra Pettke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The ongoing global pandemic of severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) is only the latest reminder of the urgent need for new antiviral strategies and diagnostic tools to improve preparedness for emergence of new pathogenic RNA-viruses. A key obstacle for the development of antivirals and diagnostic tools has been the lack of good models to study RNA viruses. LÄS MER

  5. 9. Differential Magnetic Biosensor using HTS SQUID Gradiometer

    Författare :Sobhan Sepehri; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; high-Tc SQUID; magnetic bioassay; diagnostics; RCA; microfluidics; magnetic nanoparticle; point-of-care; rolling circle amplification; differential ac susceptibility; biosensor;

    Sammanfattning : A fundamental tool for containing an epidemic outbreak and mitigating its effects is early diagnostics. Currently, most of the diagnostic tests are performed by trained staff in centralized labs, which are expensive and time-consuming to establish and operate. Lack of access to such facilities could have devastating effects. LÄS MER

  7. 10. Hantaviruses, escapees from the death row : viral mechanisms towards apoptosis resistance

    Författare :Carles Solà Riera; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Over the past decades, humanity has witnessed a constant stream of emerging pathogenic RNA viruses. The recurrent outbreaks of Ebola virus in Africa, the emergence of West Nile virus in North America and the sporadic but constant outbreaks of hantaviruses and arenaviruses are some examples of current public health concerns. LÄS MER