Sökning: "magnetic bioassay"

Hittade 3 avhandlingar innehållade orden magnetic bioassay.

  1. 1. Differential Magnetic Biosensor using HTS SQUID Gradiometer

    Författare :Sobhan Sepehri; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; high-Tc SQUID; magnetic bioassay; diagnostics; RCA; microfluidics; magnetic nanoparticle; point-of-care; rolling circle amplification; differential ac susceptibility; biosensor;

    Sammanfattning : A fundamental tool for containing an epidemic outbreak and mitigating its effects is early diagnostics. Currently, most of the diagnostic tests are performed by trained staff in centralized labs, which are expensive and time-consuming to establish and operate. Lack of access to such facilities could have devastating effects. LÄS MER

  2. 2. Detection of Biomolecules Using Volume-Amplified Magnetic Nanobeads

    Författare :Teresa Zardán Gómez de la Torre; Maria Strømme; Peter Svedlindh; Mikkel Fougt Hansen; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Magnetic biosensor; magnetic nanobeads; Brownian relaxation; padlock probe; rolling circle amplification; DNA detection; protein detection; Engineering Science with specialization in Nanotechnology and Functional Materials; Teknisk fysik med inriktning mot nanoteknologi och funktionella material;

    Sammanfattning : This thesis describes a new approach to biomolecular analysis, called the volume-amplified magnetic nanobead detection assay (VAM-DNA). It is a sensitive, specific magnetic bioassay that offers a potential platform for the development of low-cost, easy-to-use diagnostic devices. LÄS MER

  3. 3. Ultra-sensitive measurements of magnetically labelled RCA products in a microfluidic channel using a high-Tc SQUID

    Författare :Sobhan Sepehri; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; diagnostics.; high-Tc SQUID; biosensor; magnetic nanoparticle; rolling circle amplification; magnetic bioassay;

    Sammanfattning : The development of a nucleic acid (deoxyribonucleic acid (DNA), ribonucleic acid (RNA)) bioassay based on magnetic nanoparticles (MNPs) with a high-Tc superconducting quantum interference device (SQUID) gradiometer as a magnetic readout is described. The specific binding of the MNPs to the target DNA molecules changes the MNPs size distribution and, therefore, the relaxation dynamics and is measured by magnetic ac susceptometry. LÄS MER