Sökning: "comparative genomic hybridization CGH"
Visar resultat 16 - 20 av 38 avhandlingar innehållade orden comparative genomic hybridization CGH.
16. Vaginal carcinoma : studies on etiology and prognostic factors
Sammanfattning : Primary carcinoma of the vagina (PCV) is a rare disease, with poor survival, mostly affecting elderly women. Due to its rarity the established knowledge originates from studies based on small materials, therefore little is known regarding the genesis, natural history and factors predicting the prognosis. LÄS MER
17. Investigation of the genetic basis of familial non-BRCA1/2 breast cancer
Sammanfattning : Breast cancer is the most common female malignancy in the Western world and approximately 510% of all breast cancer cases present with some degree of family history. In the mid-nineties genetic linkage analyses successfully identified two breast cancer predisposing genes, BRCA1 and BRCA2. LÄS MER
18. Clinical and molecuar studies of papillary thyroid carcinoma : with an emphasis on prognostic factors
Sammanfattning : Thyroid cancer accounts for approximately 1% of all cancers reported. In Sweden 45/100, 000 inhabitants annually present with thyroid carcinoma. There are four different variants of thyroid carcinoma: papillary thyroid carcinoma (PTC), follicular thyroid carcinoma, medullary thyroid carcinoma and anaplastic thyroid carcinoma. LÄS MER
19. Molecular genetic aspects of renal cell carcinoma development
Sammanfattning : Renal cell carcinoma (RCC) is the most common tumor of the renal parenchyma. The aim of this study was to further characterize known as well as new genetic abnormalities in a clinical material of RCC, as well as in established cell lines to gain more information about etiological and progression factors. LÄS MER
20. Uveal melanoma : cytogenetics, molecular biology and tumor immunology
Sammanfattning : Uveal melanoma is the most common primary intraocular malignancy. The metastatic spread is hematogenous and exclusively to the liver. Although eye-sparing treatments are used more frequently the tumor-related mortality in uveal melanoma is still 30-50%. Only 2% of the patients have detectable metastases at the time of diagnosis. LÄS MER