Sökning: "RET-proto-oncogene"

Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet RET-proto-oncogene.

1. 1. Immunological aspects of papillary thyroid carcinoma

   Författare :Steven D. Lucas; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Papillary thyroid carcinoma; immunology; tumor antigens; RET proto-oncogene; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

   Sammanfattning : Papillary thyroid carcinoma (PTC) is a puzzling disease. Although approximately 70% of patients with PTC have regional lymph node metastases at initial surgery, the long term survival is over 95%. LÄS MER

3. 2. Clinical and molecuar studies of papillary thyroid carcinoma : with an emphasis on prognostic factors

   Författare :Petra Kjellman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Papillary thyroid carcinoma; MIB-1; RET-proto-oncogene; RET PTC; CGH; prognosis;

   Sammanfattning : Thyroid cancer accounts for approximately 1% of all cancers reported. In Sweden 45/100, 000 inhabitants annually present with thyroid carcinoma. There are four different variants of thyroid carcinoma: papillary thyroid carcinoma (PTC), follicular thyroid carcinoma, medullary thyroid carcinoma and anaplastic thyroid carcinoma. LÄS MER

4. 3. Glial cell line-derived neurotrophic factor : expression patterns, neuronal transport, regulation, effects, and receptor dependence

   Författare :Andreas C Tomac; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :glial cell line-derived neurotrophic factor GDNF ; neurturin NTN ; persephin PSP ; c Ret proto oncogene Ret ; GPI-linked receptors for the GDNF ligand family GFRas ; transforming growth factor-B TGFB ; Parkinson s disease PD ; dopaminergic DA neurons;

   Sammanfattning : Background: The mammalian nervous system depends upon trophic proteins for survival, growth and adult maintenance. These trophic factors have also been considered as potential therapeutic agents for treating human neurodegenerative disorders. LÄS MER

5. 4. Molecular biological techniques as a tool in diagnostic pathology : Applications in B-cell lymphoproliferative disease, medullary thyroid carcinoma and cervical carcinoma

   Författare :Mansour Alemi; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; PCR-SSCP; MTC; RET mutation; Lymphoma; HPV; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Sammanfattning : Identification of malignancy associated with mutations in gene sequences requires detection ofas little as a single base difference. A powerful technique in mutation detection is polymerasechain reaction (PCR) followed by single-strand conformational polymorphism (SSCP) andsequencing. LÄS MER

7. 5. Neurotrophic signalling by GDNF and its receptors

   Författare :Miles Trupp; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Many investigators have sought a polypeptide which would alleviate the neuronal loss associated with Parkinson's disease--specifically dopaminergic neurons of the ventral mesencephalon. The survival of this population of neurons has been known for some time to be promoted by soluble factors present in the conditioned media of glial cell lines. LÄS MER