Sökning: "cis-element"

Hittade 4 avhandlingar innehållade ordet cis-element.

  1. 1. The balance of splicing : A novel insight into the splicing regulation of high-risk HPV E6 and E7 oncogenes

    Författare :Johanna Jönsson; Naoko Kajitani; Stefan Schwartz; Ola Forslund; Francesca Aguilo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; HPV; splice donor; splice acceptor; cis-element; trans-acting factor; pre-mRNA splicing; splicing regulation.; Medical Virology; Medicinsk virologi;

    Sammanfattning : HPV is associated with several cancers. The genome consists of a long control region, early (E1, E2, E4, E5, E6 and E7) and late (L1 and L2) genes. The E6 and E7 proteins prevent cells from entering apoptosis and regulate the cell cycle. A deregulated expression of these can result in malignant transformations. LÄS MER

  3. 2. Hormonal regulation of HES-1 in breast cancer cells

    Författare :Patrick Müller; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hairy and Enhancer of Split homolog 1 (HES-1) is a transcriptional repressor belonging to the basic helix-loop-helix family of proteins, and has been shown to have a pivotal role as a regulator of neurogenesis, myogenesis and hematopoiesis. HES-1 has several well conserved domains, from Drosophila to mammals, and is expressed in a variety of tissues, in both embryos and adults. LÄS MER

  4. 3. Cold Acclimation : Dissecting the plant low temperature signaling pathway using functional genomics

    Författare :Catherine Benedict; Vaughan Hurry; Matsuo Uemura; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cold acclimation; functional genomics; microarray; Populus tremula; Arabidopsis thaliana; gene voting; regulon; enhancer-blocking; Plant physiology; Växtfysiologi;

    Sammanfattning : The physiological process of cold acclimation protects plants native to the temperate regions of the world from the deleterious effects of low and freezing temperatures. This is achieved by a series of transcriptional, regulatory, and metabolic changes that enable continued growth and survival. Within minutes of exposure to temperatures below ca. LÄS MER

  5. 4. Metabolic engineering of starch synthesis in barley

    Författare :Staffan Ahlandsberg; Sadequr Rahman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; hordeum vulgare; plant breeding; starch; genetic engineering; transgenic plants; biokemi; Biochemistry;

    Sammanfattning : Starch is an important industrial raw material both for food and non-food purposes. In plants, starch is deposited in the leaf and in the storage tissues such as seed endosperm, roots or tubers. LÄS MER