Sökning: "central cord syndrome"

Visar resultat 6 - 10 av 11 avhandlingar innehållade orden central cord syndrome.

1. 6. Misfolded superoxide dismutase-1 in sporadic and familial Amyotrophic Lateral Sclerosis

   Författare :Karin Forsberg; Thomas Brännström; Irina Alafuzoff; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; SOD-1 motor neuron; protein misfolding; intranuclear; antibodies; CNS; brain; patologi; Pathology;

   Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative syndrome of unknown etiology that most commonly affects people in middle and high age. The hallmark of ALS is a progressive and simultaneous loss of upper and lower motor neurons in the central nervous system that leads to a progressive muscle atrophy, paralysis and death usually by respiratory failure. LÄS MER

3. 7. The role of substance P in respiratory control in the newborn : effects of morphine and nicotine

   Författare :Jonas Berner; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : We breathe in order to maintain oxygen, carbon dioxide and pH levels within the physiological range in response to the metabolic demands of the body. To achieve this, the respiratory control system is dependent on input from peripheral and/ central chemosensitive areas and on participation of different neuromodulator systems. LÄS MER

4. 8. Cellular and molecular factors in the pathogenesis of systemic autoimmunity and comorbidities

   Författare :Margarita Ivanchenko; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Sjögren’s syndrome (SS) and systemic lupus erythematosus (SLE) are systemic rheumatic autoimmune diseases having a major impact on patient’s wellbeing. Besides fatigue, pain and direct damage to exocrine glands in SS, and various target organs, such as skin, joints, kidneys and brain in SLE, these diseases confer an increased risk of lymphoma development and can cause an autoimmune condition in the foetus of pregnant patients, termed neonatal lupus. LÄS MER

5. 9. From gene mutation to gene expression : studies on multiple endocrine neoplasia type 1 and vascular endothelial growth factors

   Författare :Emma Tham; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Multiple endocrine neoplasia type 1; mutation detection; Vascular Endothelial Growth Factors; recombinant protein; dilated cardiomyopathy; multiple sclerosis;

   Sammanfattning : Multiple Endocrine Neoplasia type 1, MEN1, is an inherited cancer syndrome whose gene was localised to chromosome 11q13 in 1988. A number of !candidate genes were characterised before the MEN1 gene was cloned in 1997. DNA sequencing of MEN1 to search for mutations in patients is used as a complement to clinical diagnosis. LÄS MER

7. 10. Precision medicine of ovarian cancer for adults and children : molecular, hereditary and clinical aspects

   Författare :Sandra Wessman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Ovarian cancer was 2018 ranked as the eighth most common cancer diagnosis and cause of death in women. Of these, the most common histological type is high-grade serous carcinoma. LÄS MER