Sökning: "blood parasites"

Visar resultat 21 - 25 av 81 avhandlingar innehållade orden blood parasites.

  1. 21. Strategies for vaccine development applied to asexual blood-stage antigenes Pf332 and Pf155/RESA from Plasimodium falciparum

    Författare :Diana Haddad; KTH; []
    Nyckelord :;

    Sammanfattning : Development of an effective malaria vakne poses a majorscientific challenge both in the laboratory and in the field,This thesis addresses several aspects of malaria vaccinedevelopment, by focusing on two differentasexualblood stage antigens ofPlusmedium falicpanrm , Pf332and Pfl155/RESA.Antibodies play an important role in protective immunity tothis parasite. LÄS MER

  3. 22. Immunological insights into equine responses against Strongylus vulgaris : Ex vivo studies using equine intestinal organoids and blood mononuclear cells

    Författare :Stina Hellman; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Anthelminthic drugs have controlled parasitic infections in veterinary species for decades, but today this use is questioned due to concerns about antimicrobial resistance. For most microorganisms, a feasible alternative is vaccination but for parasites, commercial vaccines are scarce. LÄS MER

  4. 23. PCR adjusted cure rates in clinical trials of antimalarial drugs in Africa : influence of extended follow-up and consecutive day blood sampling

    Författare :Andreas Mårtensson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria treatment guidelines are based primarily on results from clinical trials. Accurate assessment of drug efficacy in such studies therefore represents a prerequisite to ensure effective and lifesaving treatment for children with Plasmodium falciparum infections in Africa. LÄS MER

  5. 24. Variant antigens at the infected red cell surface in Plasmodium falciparum malaria

    Författare :Victor Fernandez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Plasmodium falciparum; blood stages; variant antigens; var PfEMP1; rif RIFIN; adhesive phenotypes; cytoadherence; endothelial receptor; PECAM-1 CD31; rosetting; heparan sulphate;

    Sammanfattning : Disease severity in Plasmodium falciparum infections is, to a large extent, a consequence of the parasite's efficient escape from die human host defences. Sequestration and antigenic variation are two evasion mechanisms featured by P.falciparum. LÄS MER

  7. 25. Malaria and polypeptides of Plasmodium falciparum at the infected erythrocyte surface

    Författare :Mia Palmkvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria is one of the top three most lethal infectious diseases in the world after tuberculosis and HIV. The disease is caused by intracellular parasites of the genus Plasmodium spp. LÄS MER