Sökning: "Unexpected death"

Visar resultat 21 - 25 av 37 avhandlingar innehållade orden Unexpected death.

  1. 21. Neurothrophins during development : overexpression in neural stem cells

    Författare :Thomas Ringstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The neurotrophins constitute a family of secreted, diffusible peptide factors that are widely expressed in the developing nervous system. They are known to function as survival factors in the peripheral nervous system during the period of naturally occurring cell death, to promote axonal outgrowth and to affect neurotransmitter expression of responsive cells. LÄS MER

  3. 22. Heparan Sulfate and Development : A Study of NDST Deficient Mice and Embryonic Stem Cells

    Författare :Katarina Holmborn; Lena Kjellén; Erik Forsberg; Catherine L. Merry; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell and molecular biology; heparan sulfate; proteoglycan; biosynthesis; N-deacetylase N-sulfotransferase; NDST; gene targeting; embryonic development; lung development; mast cells; Cell- och molekylärbiologi;

    Sammanfattning : Heparan sulfate (HS) proteoglycans consist of sulfated HS chains covalently bound to core proteins. They are ubiquitously expressed, on the cell surface and in the extracellular matrix, throughout the body. LÄS MER

  4. 23. All-Photonic Control of Biorelevant Processes using Molecular Photoswitches and Caged Compounds

    Författare :Jesper Nilsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dithienylethene; azobenzene; drug release; kinase inhibitor; spiropyran; caged compound; live cell; spectroscopy; o-nitrobenzyl; photoswitch;

    Sammanfattning : The development of light-controlled molecular tools for in situ regulation of biological activity holds great promise e.g. for resolving dynamic aspects of cellular signal transduction and to overcome inherent pharmaceutic limitations such as poor drug selectivity. LÄS MER

  5. 24. Early Detection and Treatment for Children : Experiences and outcome of implementation at a pediatric hospital

    Författare :Ann-Charlotte Almblad; Mats Målqvist; Gunn Engvall; Inger Hallström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PEWS; Pediatric; Clinical deterioration; inter-professionell; teamwork; ACT; PARiHS; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Early recognition of severely ill children is necessary to prevent serious adverse events and unexpected death. To promote patient safety the Early Detection and Treatment Program for Children (EDT-C) was developed at a University Children’s Hospital in Sweden. LÄS MER

  7. 25. Computational studies of photodynamic drugs, phototoxic reactions and drug design

    Författare :Klefah Abrahem Klefah Musa; Leif Eriksson; Nino Russo; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NSAIDs; fluoroquinolone; photodegradation; phototoxicity; drug design; DFT; TD-DFT; Biophysical chemistry; Biofysikalisk kemi; Chemistry; Kemi;

    Sammanfattning : The most important criterion when designing new drugs or improving old ones in order to prevent side effects or at least diminish them is drug safety. Treatment of all diseases generally needs use of either topical application or systemic medications (transported in the blood) during a certain period of time. LÄS MER