Sökning: "Tissue degeneration"
Visar resultat 1 - 5 av 96 avhandlingar innehållade orden Tissue degeneration.
1. Shoulder impingement; Evaluation of the clinical outcome, radiographic findings, histology, ultrastructure and biochemistry
Sammanfattning : This thesis had two main purposes: on the one hand, to assess and evaluate the clinical outcome of different treatment strategies for subacromial impingement syndrome (SAIS), in both the short and the long term and, on the other hand, to investigate and illuminate the pathophysiology of the syndrome in terms of the radiographic, histological, ultrastructural and biochemical appearance. In Study I, the clinical outcome was assessed two to three years after intervention, in patients with SAIS who underwent either surgical (subacromial decompression using the open or arthroscopic technique) or non-surgical treatment. LÄS MER
2. rd1 Photoreceptor Degeneration: Photoreceptor Rescue and Role of Metalloproteases in Retinal Degeneration
Sammanfattning : The thesis is focused on an attempt to delay photoreceptor cell death in the rd1 mouse using Lens Epithelium Derived Growth Factor (LEDGF), Glutathione S-Transferase mu (GST-?? and Glutathione S-Transferase alpha (GST-?? in an organ culture paradigm as well as the role of metalloproteases (MMPs) and their tissue inhibitors in photoreceptor degeneration (TIMPs). The rd1 mouse model displays a retina degeneration which starts around day 10 with rod photoreceptor cell death. LÄS MER
3. Diffusion in Bone Tissue
Sammanfattning : In order to prevent or modify the processes of bone degeneration the modeling and remodeling of bone tissue must be better understood. In this thesis it is assumed that the primary condition leading to bone growth is a change of the chemical environment caused by transport of matter resulting from stress driven diffusion. LÄS MER
4. Intervertebral disc degeneration in dogs
Sammanfattning : Back pain is common in both dogs and humans, and is often associated with intervertebral disc (IVD) degeneration. The IVDs are essential structures of the spine and degeneration can ultimately result in diseases such as IVD herniation or spinal instability. LÄS MER
5. Imaging of tissue degeneration in knee osteoarthritis using magnetic resonance and synchrotron radiation
Sammanfattning : Osteoarthritis (OA) is a very common disease, especially in the knee. It is characterized by the breakdown of articular cartilage but involves all parts of the joint. OA is usually diagnosed at a late stage when the articular cartilage has begun to disappear. What happens before these macroscopic alterations is to alarge extent unknown. LÄS MER