Sökning: "TCR usage"

Visar resultat 16 - 20 av 22 avhandlingar innehållade orden TCR usage.

1. 16. Regulatory immune responses in humans naturally primed to Plasmodium falciparum or vaccinated with tetanum toxoid or purified protein derivative

   Författare :Gehad Elghazali; Thor Grundtvig Theander; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; immunologi; Immunology;

   Sammanfattning : It is well established that the balance between functionally distinct regulatory CD4+ T cells plays a major role in the development of immunity and/or pathogenesis to many different infections. In spite of the importance of Th lineage commitment in disease, the critical questions how the balance between Th1 and Th2 cells is regulated is largely unresolved. LÄS MER

3. 17. Heavy Metal Superantigen : Genetic Regulation of Lymphocyte Activation by HgC12

   Författare :Yun Jiang; Peter Mathieson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; immunologi; Immunology;

   Sammanfattning : Injections of subtoxic doses of HgCl2 (mercuric chloride) cause a systemic autoimmune disease in genetically predisposed rats and mice. My work was designed to elucidate how HgCl2 induces lymphocyte activation and how the response to HgCl2 is regulated in susceptible and resistant strains. LÄS MER

4. 18. The T cell phenotype and receptor repertoire in different stages of rheumatoid arthritis : an immunological timeline

   Författare :Sara Turcinov; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Rheumatoid arthritis (RA) is a systemic autoimmune disease, characterized by symmetrical inflammation in hands and feet. Antibodies recognizing citrullinated protein (ACPA) and/or rheumatoid factor (RF) are found in most patients and associates with a worse prognosis. Genetic predisposition (i.e. LÄS MER

5. 19. Immunity against porcine islet xenografts in man

   Författare :Ellinor Lindeborg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Pig islets xenotransplantation; Type 1 diabetes; xenoimmune antibodies; IgG1; T cells.;

   Sammanfattning : Due to the lack of organs for clinical transplantation, alternative sources have been investigated. One solution to this shortage could be xenotransplantation, i.e. the transplantation of organs/cells across species barriers. LÄS MER

7. 20. Genetics and functions of innate-like lymphocyte subsets

   Författare :Julia Rolf; Göteborgs universitet; []
   Nyckelord :innate-like lymphocyte; CD1d; autoimmunity; genetic mapping; microarray; Salmonella infection;

   Sammanfattning : The immune system contains three different branches: innate immunity, adaptive immunity and innate-like lymphocytes that share properties both with the innate and adaptive immune cells. The innate-like lymphocytes have the capacity to rapidly become activated by invading pathogens and also to modulate immune responses and thereby inhibit or promote inflammation. LÄS MER