Sökning: "S1P Sphingosine-1-phosphate"
Hittade 5 avhandlingar innehållade orden S1P Sphingosine-1-phosphate.
1. Intestinal immune cells in health and disease. Dissecting histological characteristics of inflammatory bowel disease and inflamed lung using quantitative immunohistochemical image analysis
Sammanfattning : .... LÄS MER
2. The ApoM/S1P-complex: its role in vascular inflammatory disease and interaction with S1P-receptors
Sammanfattning : HDL is believed to be protective against cardiovascular disease (CVD) via the reverse cholesterol transport and anti-inflammatory actions in the vessel. Apolipoprotein M (apoM) is an apolipoprotein mainly associated with HDL. Recently ApoM was proven tobe the main carrier of Sphingosine 1-phosphate (S1P) in circulation. LÄS MER
3. The role of N-cadherin and S1P/S1P1 in pancreas development
Sammanfattning : Organogenesis of epithelial organs requires interaction between epithelial and mesenchymal tissues. During pancreas development, mesenchyme-derived structures induce specification, growth and differentiation of pancreatic epithelial cells. LÄS MER
4. Mechanisms of platelet-mediated fibroblast proliferation
Sammanfattning : Wound healing is a multicomponent event that involves a network of molecular and cellular crosstalk between cells, including leukocytes, platelets and fibroblasts. Despite increased knowledge over the past decades regarding the regulation of cell and tissue growth, the inter- and intracellular systems that control wound healing are incompletely understood. LÄS MER
5. On the role of bioactive sphingolipids and their metabolizing enzymes in cancer
Sammanfattning : Ceramide is a family of closely related molecules, which are presumed to be in the center of sphingolipid metabolism. Among sphingolipid metabolites, several ceramide subspecies and sphingosine induce apoptosis, cell cycle arrest and death, whereas sphingosine 1-phosphate (S1P) mediates cell proliferation, invasion, angiogenesis and metastasis. LÄS MER