Sökning: "Roza"
Hittade 5 avhandlingar innehållade ordet Roza.
1. Genetic, epigenetic and environmental factors of importance for CYP1A2 catalyzed drug metabolism
Sammanfattning : The heme containing cytochrome P450 (CYP450) enzymes participate in the phase I metabolism of drugs and other xenobiotics as well as endogenous substrates. CYP1A2 is one of the major CYP450 enzymes and account for about 13% of the total CYP450 content in the liver and is responsible for the metabolism of several clinically used drugs, e. LÄS MER
2. Globalization and Development : The Impact of International Trade on Political and Social Institutions
Sammanfattning : The Impact of Trade Liberalization in the Presence of Political DistortionsPolitical distortions are prevalent in many developing countries and can imply substantial productivity losses. Theory is ambiguous as to whether greater openness to trade amplifies or reduces the effects of such distortions. LÄS MER
3. Thrombin generation in different cohorts : Evaluation of the haemostatic potential
Sammanfattning : The aim of this thesis is to evaluate thrombin generation in patients with thrombophilia (Paper I), in patients with venous thromboembolism (Paper II), in healthy women during the menstrual cycle (Paper III), in patients with liver disease (Paper IV) and in patients with mild deficiency of factor VII (Paper V).For this purpose, thrombin generation was measured in platelet poor plasma by the calibrated automated thrombogram (CAT®) assay. LÄS MER
4. On Credibility Assessment in Aircraft System Simulation
Sammanfattning : The aeronautical industry is becoming increasingly reliant on Modeling and Simulation (M&S) for use throughout all system development phases, for system verification, and end-user training. To justify and to utilize the full potential of today’s model-based approach, the development of efficient and industrially applicable methods for credibility assessment of M&S efforts is a key challenge. LÄS MER
5. Corruption, Distortions and Development
Sammanfattning : Essay I: Does increased government transparency make bureaucracies more meritocratic? I study the impact of politician disclosure requirements on the assignment of bureaucrats to public posts. I collect detailed information on bureaucrats' qualifications and construct a novel measure of bureaucratic mismatch—an index measuring the extent to which a bureaucrat is under- or overqualified to perform a specific task. LÄS MER