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Visar resultat 1 - 5 av 127 avhandlingar som matchar ovanstående sökkriterier.

1. 1. On Phase Behaviours in Lipid/Polymer/Solvent/Water Systems and their Application for Formation of Lipid/Polymer Composite Particles

   Författare :Anna Imberg; Per Hansson; Krister Thuresson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; Biodegradable; CLSM; Composite Particles; Controlled Release; Cubic Phases; Drug Delivery; Flory-Huggins Theory; FT-PGSE-NMR; IPMS; Liquid Phase; Lipid Domains; Liquid Handler; Microspheres; Microstructure; Phase Behaviour; Phase Separation; Polymer Matrix; SAXS; Segregation; Sponge Phase; Swelling; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; fysikalisk och oorganisk farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry;

   Sammanfattning : A new kind of lipid/polymer composite particle, consisting of a biodegradable polymer matrix with well-defined lipid domains, has been created. The lipid used is the water-swelling lipid monoolein (MO), which forms a reversed bicontinuous cubic diamond structure in aqueous solutions. LÄS MER

3. 2. Reversed phase ion-pair liquid chromatography : studies of adsorption equilibria and equilibrium disturbances

   Författare :Anders Sokolowski; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

   Sammanfattning : .... LÄS MER

4. 3. Reversed-phase ion-pair partition chromatography

   Författare :Karl-Gustav Wahlund; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

   Sammanfattning : .... LÄS MER

5. 4. Modeling and Optimization of Reversed-Phase Chromatography : Effects of Modulators and Temperature

   Författare :Karolina Arkell; Avdelningen för kemiteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Reversed-phase chromatography; Hydrophobic interaction chromatography; Mechanistic modeling; INSULIN; KCl; Ethanol; Temperature; Multi-objective optimization; Constraint; Solubility;

   Sammanfattning : Many widespread diseases, such as diabetes, various types of cancer, and aggressive versions of influenza, are treated or prevented with biopharmaceuticals. Biopharmaceuticals are drugs that are based on proteins, peptides, antibodies, attenuated viruses (vaccines), and other biomolecules that are synthesized predominately in bacteria, yeast, and mammalian cells. LÄS MER

7. 5. FACING THE CHALLENGE OF SKIN PENETRATION - A STUDY ON LIPIDIC LIQUID CRYSTALLINE PHASES FOR DERMAL DRUG DELIVERY

   Författare :Hanne Evenbratt; Chalmers tekniska högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 5-diol; liquid crystalline phases; N-Methyl-2-pyrrolidone; pentane-1; glyceryl monooleat; propylene glycol; dermal drug delivery; glyceryl monooleyl ether; cubic phase; reversed hexagonal phase;

   Sammanfattning : The skin is a barrier which protects us against daily attacks of foreign substances. From a pharmaceutical perspective it is also an interesting delivery route with its large surface and possibility to reach the blood stream circumventing first passage metabolism. With the varied size, structure etc. LÄS MER