Sökning: "Lipid Domains"

Visar resultat 1 - 5 av 73 avhandlingar innehållade orden Lipid Domains.

  1. 1. Lipid bilayers versus monolayers- Sponge phases and skin lipid domains

    Författare :Katarina Ekelund; Livsmedelsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; fatty acids; Langmuir-Blodgett films; AFM; domains; stratum corneum; bilayer curvature; lipids; glycerol monooleate; phase behaviour; sponge phase; L3 phase; Livsmedelsteknik; cholesterol; Food and drink technology;

    Sammanfattning : The L3, or sponge, phase is a thermodynamically stable isotropic liquid consisting of a surfactant membrane in aqueous solution. A solvent induced L3 phase is shown in systems of solvent, monoolein and water. LÄS MER

  3. 2. On Phase Behaviours in Lipid/Polymer/Solvent/Water Systems and their Application for Formation of Lipid/Polymer Composite Particles

    Författare :Anna Imberg; Per Hansson; Krister Thuresson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; Biodegradable; CLSM; Composite Particles; Controlled Release; Cubic Phases; Drug Delivery; Flory-Huggins Theory; FT-PGSE-NMR; IPMS; Liquid Phase; Lipid Domains; Liquid Handler; Microspheres; Microstructure; Phase Behaviour; Phase Separation; Polymer Matrix; SAXS; Segregation; Sponge Phase; Swelling; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; fysikalisk och oorganisk farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry;

    Sammanfattning : A new kind of lipid/polymer composite particle, consisting of a biodegradable polymer matrix with well-defined lipid domains, has been created. The lipid used is the water-swelling lipid monoolein (MO), which forms a reversed bicontinuous cubic diamond structure in aqueous solutions. LÄS MER

  4. 3. Structural studies of proteins in apoptosis and lipid signaling

    Författare :Maria Dolores Herman Moreno; Pär Nordlund; Markus Gruetter; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; proteins; crystal structure; apoptosis; cancer; CoFi-Blot; kinases; lipid signaling; Structural biology; Strukturbiologi; Structural Biology; strukturbiologi;

    Sammanfattning : Signaling pathways control the fate of the cell. For example, they promote cell survival or commit the cell to death (apoptosis) in response to cell injury or developmental stimuli, decisions, which are vital for the proper development and functioning of metazoan. LÄS MER

  5. 4. Adaptive mechanisms in the hypoxic tumor microenvironment. Functional role of proteoglycans and identification of potential treatment targets

    Författare :Julien Menard; Tumörmikromiljö; []
    Nyckelord :Hypoxia; Acidosis; Proteoglycans; Endocytosis; Glioblastoma; Lipid; Caveolin-1; Antibody-drug conjugate;

    Sammanfattning : Cancer cells reside in a complex microenvironment comprising stromal cells and immune cells embedded in an extracellular matrix (ECM). Early on in tumor progression, cells reach a critical volume beyond which blood supply is impaired, leading to a decrease in oxygen levels (hypoxia) and nutrient supply. LÄS MER

  7. 5. Phase Transformations in Solid Pharmaceutical Materials Studied by AFM, ESCA, DSC and SAXS

    Författare :Denny Mahlin; Göran Alderborn; Sven Engström; Duncan Q M Craig; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; polymer; lipid; lactose; phase transformation; phase formation; crystallisation; AFM; X-ray diffraction; ESCA; DSC; solid dispersion; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi;

    Sammanfattning : Mixing excipients is a common way to produce pharmaceutical materials with suitable properties for drug formulation. An understanding of the basic mechanisms involved in the formation and transformation of the structures of solid state mixtures is crucial if one is to be able to produce materials with the desired properties in a reliable way. LÄS MER