Sökning: "RNAi RNA-interference"

Visar resultat 11 - 15 av 36 avhandlingar innehållade orden RNAi RNA-interference.

  1. 11. Systemic RNAi Relies on the Endomembrane System in Caenorhabditis elegans

    Författare :Yani Zhao; Andrea Hinas; Staffan Svärd; Simon Tuck; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Systemic RNAi; RNAi inheritance; late endosomes MVBs; SID-5; SEC-22; SYX-6; C12D8.1; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : The membrane system of a eukaryotic cell is a large and complex system handling the transport, exchange and degradation of many kinds of material. Recent research shows that double-stranded RNA (dsRNA) mediated gene silencing (RNA interference) is a membrane related process. LÄS MER

  3. 12. Molecular and diagnostic aspects of the protein p41 of HHV-6 and silencing of the CD46 receptor by RNA interference

    Författare :Yunhe Xu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Human herpesvirus 6; p41; multiple sclerosis; RNA interference; small interfering RNAs; CD46;

    Sammanfattning : Multiple sclerosis (MS) is one of the most common diseases of the central nervous system (CNS), leading to sensory and motor disability in young adults. There is no efficient treatment of the disease. Its etiology is unknown. LÄS MER

  4. 13. miRNA and Asymmetric siRNA : Small RNAs with Large Effects on Bone Metabolism

    Författare :Navya Laxman; Andreas Kindmark; Sara Windahl; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; miRNA; cp-siRNA; RNAi; bone; Osteoblast; Sequencing; Differential expression; Wnt pathway; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : RNA interference (RNAi) is a post-transcriptional gene silencing process elicited by double-stranded RNA, such as micro-RNA (miRNA) and small interfering RNA (siRNA). They are 18-25 nucleotide long, small non-coding RNAs acting as critical regulators in eukaryotic genome expression. LÄS MER

  5. 14. Development of Transgenic Potatoes to Attain Novel Starch Qualities

    Författare :Mariette Andersson; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Livsmedelsteknik; Food and drink technology; Biokemisk teknik; Biochemical technology; StGH; starch yield; RNAi; antisense; gene silencing; ahas; potato transformation; sbe2; sbe1; gbss; amylopectin; amylose; Starch; potato;

    Sammanfattning : Starch is a plant-derived polysaccharide with many uses in different food and non-food applications. In this thesis, the production of two novel potato starch qualities, amylopectin and high-amylose, and the modifications and the characteristics of the produced plants and starches are described. LÄS MER

  7. 15. Molecular dissection of Bruton’s tyrosine kinase signaling in hematopoietic cells using RNAi

    Författare :Juhana E Heinonen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : RNA mediated gene silencing, RNA interference (RNAi), has recently been identified in mammalians. This thesis describes the utilization and development of RNAi based tools for signal transduction research. The effects of Bruton s tyrosine kinase (Btk) down-regulation with RNAi have been studied with gene expression profiling in hematopoietic cells. LÄS MER