Sökning: "Pher Andersson"

Visar resultat 16 - 20 av 26 avhandlingar innehållade orden Pher Andersson.

1. 16. Reactivity and Selectivity Studies in Iridium-Catalyzed Asymmetric Hydrogenation

   Författare :Bram B. C. Peters; Pher G. Andersson; Xavier Verdaguer; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Asymmetric hydrogenation; Chemoselectivity; Enantioconvergency; Iridium catalysis; Multi-reduction; Organic Chemistry; organisk kemi;

   Sammanfattning : Transition-metal catalyzed stereoselective hydrogenation constitutes an indispensable method for the preparation of chiral molecules. The work in this thesis describes the development of efficient catalytic asymmetric hydrogenations with a focus on the elucidation of reactivity patterns and chemoselectivity in hydrogenations. LÄS MER

3. 17. Iridium Catalysed Asymmetric Hydrogenation of Olefins and Isomerisation of Allylic Alcohols

   Författare :Byron Peters; Pher Andersson; Andreas Pfaltz; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; organisk kemi; Organic Chemistry;

   Sammanfattning : The work described in this thesis is focused on exploring the efficacy of asymmetric iridium catalysis in the hydrogenation of challenging substrates, including precursors to chiral sulfones and chiral cyclohexanes. Furthermore, iridium catalysis was used to isomerise allylic alcohols to aldehydes, and in a formal total synthesis of Aliskiren (a renin inhibitor). LÄS MER

4. 18. Hydrogenation, Transfer Hydrogenation and Hydrogen Transfer Reactions Catalyzed by Iridium Complexes

   Författare :Xu Quan; Pher Andersson; Jonathan Williams; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Iridium catalyst; carbene; N; P - ligand; asymmetric hydrogenation; transfer hydrogenation; hydrogen transfer reaction; alkylation; olefin; ketone; amide; organisk kemi; Organic Chemistry;

   Sammanfattning : The work described in this thesis is focused on the development of new bidentate iridium complexes and their applications in the asymmetric reduction of olefins, ketones and imines. Three new types of iridium complexes were synthesized, which included pyridine derived chiral N,P-iridium complexes, achiral NHC complexes and chiral NHC-phosphine complexes. LÄS MER

5. 19. The Use of N,P-Iridium and N,P-Palladium Complexes in Asymmetric Synthesis

   Författare :Wangchuk Rabten; Pher Andersson; Virginie Vidal; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Iridium; Asymmetric Hydrogenation; Palladium; Asymmetric Cycloisomerization and Hosomi-Sakurai Allylation; organisk kemi; Organic Chemistry;

   Sammanfattning : The work presented in this thesis concerns asymmetric catalysis using chiral N,P-ligands and iridium or palladium transition metals. The first part  (Chapters 2 and 3) highlights the N,P-iridium catalyzed asymmetric hydrogenation of 1,4-cyclohexadienes having functionalized or unfunctionalized substituents, including allylsilane side chains. LÄS MER

7. 20. Synthesis and Evaluation of N,P-Chelating Ligands in Asymmetric Transition-Metal-Catalyzed Reactions : Ir-Catalyzed Asymmetric Hydrogenation and Pd-Catalyzed Asymmetric Intermolecular Heck Reaction

   Författare :Päivi Tolstoy; Pher G. Andersson; Göran Hilmersson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Asymmetric hydrogenation; Heck reaction; N; P ligand; Iridium; Palladium; Asymmetric catalysis; Alkenes; Fluorine; Diarylmethine stereocenters; Chemistry; Kemi; organisk kemi; Organic Chemistry;

   Sammanfattning : This thesis describes synthesis of new chiral N,P ligands and their evaluation in two types of asymmetric transition-metal catalyzed reactions. The first part of the thesis describes studies in iridium-catalyzed asymmetric hydrogenation. LÄS MER