Sökning: "Fluorine"

Visar resultat 1 - 5 av 98 avhandlingar innehållade ordet Fluorine.

  1. 1. Development of new Fluorination Methods Directed to Fluorine-18 Labelling

    Författare :Miguel Ángel Cortés González; Kálmán J. Szabó; Guosheng Liu; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fluorine; fluorine-18; late-stage; labelling; nucleophilic; electrophilic; fluorination; positron emision tomography; PET; hypervalent iodine; benziodoxole; metal-free; DBU; copper; palladium; rhodium; carbene; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis deals with the development of new fluorination reactions and their application to fluorine-18 labelling. Fluorine-18 labelled compounds are employed as tracers in Positron Emission Tomography (PET), which is a powerful non-invasive imaging method in medical diagnostics. LÄS MER

  3. 2. Synthesis of Organofluorine Compounds and Allenylboronic Acids - Applications Including Fluorine-18 Labelling

    Författare :Denise N. Meyer; Kálmán J. Szabó; Dominique Cahard; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; boron; allenylboronic acid; BINOL; homopropargyl alcohol; organocatalyst; organoboron; organofluorine; fluorine; fluorine-18; late-stage; labelling; labeling; nucleophilic; electrophilic; fluorination; positron emision tomography; PET; radiotracer; hypervalent iodine; benziodoxole; benzoxazepines; diaryliodonium salt; metal-free; neutrophil elastase; NE; neutrophil elastase inhibitor; trifluoromethylation; trifluoromethylthiolation; difluoro enol silyl ethers; organisk kemi; Organic Chemistry;

    Sammanfattning : This work is focused on two areas: the chemistry of organofluorine and organoboron compounds. In the first chapter, a copper-catalysed synthesis of tri- and tetrasubstituted allenylboronic acids is presented. Extension of the same method leads to allenylboronic esters. LÄS MER

  4. 3. Bifunctionalization of Small Organic Molecules Based on Fluorine Incorporation

    Författare :Marvin Lübcke; Kálmán Szabó; Ryan Gilmour; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fluorination; fluorocyclization; fluorine chemistry; trifluoromethylthiolation; rhodium-catalysis; organocatalysis; asymmetric synthesis; hypervalent iodine; multicomponent reaction; bifunctionalization; diazo compounds; organisk kemi; Organic Chemistry;

    Sammanfattning : The dissertation work that is summarized in this thesis describes novel syntheses of organofluorine compounds with a broad coverage of different fluorine-containing motifs.Chapter 2.1 covers works on the exploration of new trifluoromethylthiolating reactions of diazocarbonyl compounds. LÄS MER

  5. 4. Fluoride in surface water and groundwater in southeast Sweden : sources, controls and risk aspects

    Författare :Tobias Berger; Mats E. Åström; Pasi Peltola; Henrik Drake; Olle Selinus; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fluorine; fluoride; water-rock interaction; granite; crystalline bedrock; surface water; groundwater; Götemar; drinking water quality; aluminium; speciation; fluorosis; PBA; Miljövetenskap; Environmental Science;

    Sammanfattning : The aim of this thesis is to determine the sources, controls and risk aspects of fluoride in surface water and groundwater in a region of southeastern Sweden where the fluorine-rich 1.45 Ga circular Götemar granite (5 km in diameter) crops out in the surrounding 1.8 Ga granites and quartz monzodiorites (TIB rocks). LÄS MER

  7. 5. Synthesis and Evaluation of N,P-Chelating Ligands in Asymmetric Transition-Metal-Catalyzed Reactions : Ir-Catalyzed Asymmetric Hydrogenation and Pd-Catalyzed Asymmetric Intermolecular Heck Reaction

    Författare :Päivi Tolstoy; Pher G. Andersson; Göran Hilmersson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Asymmetric hydrogenation; Heck reaction; N; P ligand; Iridium; Palladium; Asymmetric catalysis; Alkenes; Fluorine; Diarylmethine stereocenters; Chemistry; Kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis describes synthesis of new chiral N,P ligands and their evaluation in two types of asymmetric transition-metal catalyzed reactions. The first part of the thesis describes studies in iridium-catalyzed asymmetric hydrogenation. LÄS MER