Sökning: "PRDM16"

Hittade 3 avhandlingar innehållade ordet PRDM16.

  1. 1. Spatial and temporal regulation of neural stem cells in the developing brain by PRDM16

    Författare :Li He; Qi Dai; Christos Samakovlis; Simon Hippenmeyer; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain development; Neural stem cell; PRDM16; BMP signaling; Choroid plexus; Cortical neurogenesis; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The mammalian brain comprises a large number and diversity of neurons and non-neural cells. Most of these cell types derive from a single sheet of neuroepithelium (NE) that contains a limited pool of neural stem cells (NSCs).  NSCs in the developing brain are under complex regulation to achieve maximum daughter cell type diversity. LÄS MER

  3. 2. On genes involved in common neurological disorders : focus on Parkinson's disease

    Författare :Caroline Ran; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Parkinson’s disease and migraine are complex neurological disorders and it is likely that a combination of genetic risk factors are involved in the etiology of both these diseases. Papers in this thesis investigate candidate genes in the search of genetic risk factors contributing to disease. LÄS MER

  4. 3. Deciphering the role of genetics and circadian rhythm in cluster headache

    Författare :Carmen Fourier; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cluster headache (CH) is a complex neurovascular disorder with a distinct circadian attack pattern. Although many aspects of the disease’s pathophysiology remain to be elucidated, it is likely caused by a combination of different genetic and environmental risk factors. LÄS MER