Sökning: "NFkB"

Visar resultat 21 - 23 av 23 avhandlingar innehållade ordet NFkB.

1. 21. New aspects on retinoic acid induced HL-60 granulocytic differentiation

   Författare :Agnè Kulytè; Tor Olofsson; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The underlying mechanisms of myeloid cell differentiation are still not entirely elucidated. It is therefore an urgent task to extent the basis for a comprehensive model of granulocytes differentiation. A primary goal for studies has been the identification of differentiation markers. LÄS MER

3. 22. Statin-induced cellular effects mediated by the P2X7 receptor

   Författare :Oras Mistafa; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Cholesterol-lowering statins have been shown to inhibit growth of different cancer cells both in vitro and in vivo. Epidemiological studies also indicate a chemopreventive effect of statins. We have investigated the effect of statins on Akt/protein kinase B signaling and their sensitizing effect of cytostatic drugs. LÄS MER

4. 23. Regulation of HIV-1 provirus transcription

   Författare :Mojgan H Naghavi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Key words- HIV-1; LTR; transcription; subtypes; phylogenetic analysis; NFkappaB; USF; MCEF; HMG-1 DSP1; Dorsal.;

   Sammanfattning : Transcription of the HIV-genome is regulated by the interaction of viral long terminal repeat (LTR) cis-acting sequences with a complex of viral regulatory proteins and cellular transcription factors. The complex interplay between the cellular-, and/or viral proteins and LTR of different subtypes may play a role in the control of HIV-1 latency versus activation. LÄS MER