Sökning: "Matrigel"

Visar resultat 6 - 10 av 20 avhandlingar innehållade ordet Matrigel.

  1. 6. The role of androgen in prostate cancer cell invasion

    Författare :Yin-Choy Chuan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostate cancer (PCa) is the most commonly diagnosed cancer in men in developed countries. Androgen deprivation therapy (ADT) is the mainstay treatment for patient diagnosed with PCa. However, the cancer will eventually relapse with metastatic cancer and become resistant to the treatment. LÄS MER

  2. 7. Engraftment and tolerance induction in cellular therapy : focus on mesenchymal stromal cells

    Författare :Karin Ljung; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Different cell types have been employed in the search for a cellular therapy that is applicable for the treatment of heart failure. Remuscularization strategies using stem-cell-derived cardiomyocytes have been prone to arrhythmias. LÄS MER

  3. 8. Adaptive Immunity in Cardiovascular Disease

    Författare :Daniel Engelbertsen; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Atherosclerosis, thickening of the major arteries, is a chronic disease leading to cardiovascular disease (CVD) such as myocardial infarction (MI) and stroke, both affecting millions worldwide. T-cells and antibodies have been implicated in atherosclerosis. LÄS MER

  4. 9. Crosstalk between colorectal cancer cells and tumour-associated macrophages

    Författare :Yuan Zhang; Malmö Cellpatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD47; tumour-associated macrophage; matrix metalloproteinase; cell migration; colon cancer;

    Sammanfattning : Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of death from cancer worldwide. People suffering from inflammatory bowel disease, such as Crohns’ disease and ulcerative colitis, are at an increased risk of developing CRC. The development of CRC is highly influenced by the tumour microenvironment. LÄS MER

  5. 10. Use of primary human hepatocytes for the elucidation of bile acid synthesis

    Författare :Ewa C S Ellis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In the present investigation we cultured primary human hepatocytes on matrigel under serum-free conditions and studied bile acid formation. The following observations were made: · The major steroid products excreted from primary human hepatocytes into the culture medium were cholic acid, CA (70%) and chenodeoxycholic acid, CDCA (25%) conjugated with glycine or taurine. LÄS MER