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Visar resultat 21 - 25 av 64 avhandlingar som matchar ovanstående sökkriterier.

  1. 21. Studies on leukotriene B4 and alarmins in inflammatory responses

    Författare :Min Wan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Leukotriene B4 (LTB4) is a potent proinflammatory lipid mediator that is involved in host defense and inflammatory diseases, such as atherosclerosis. LL-37 and heparin binding protein (HBP) are cationic antimicrobial polypeptides, which belong to the alarmin family known to promote innate and adaptive immune reactions in response to tissue infection or injury. LÄS MER

  3. 22. Antimicrobial peptides and eicosanoids : roles and interactions in inflammation and host defense

    Författare :Xiao Tang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Antimicrobial peptides (AMPs) have a broad spectrum of activities and exert their functions by both direct killing of microbes through the interaction with the microbial membrane, and modulation of innate and adaptive immunity of the host. In humans, cathelicidins and defensins represent the major families of AMPs. LÄS MER

  4. 23. Role of antimicrobial peptides in tuberculosis and respiratory tract infections : clinical and mechanistic studies

    Författare :Rokeya Sultana Rekha; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Antimicrobial peptides (AMPs) are effector molecules of the innate immune system in multicellular organisms. They are mainly expressed in epithelial cells and immune cells, providing the first line of defense against a wide range of pathogens. LÄS MER

  5. 24. Antimicrobial peptides in innate immunity : interactions with antibiotics and effects of post-translational modifications

    Författare :Salma Al Adwani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cationic antimicrobial peptides (AMPs) are important innate immunity factors contributing to the clearance of invading pathogens and immunomodulating immune responses. In this thesis, the focus is on AMPs of the cathelicidin family, i.e. the human LL-37 and the canine K9CATH. LÄS MER

  7. 25. Protein and lipid interactions of mammalian antibacterial peptides

    Författare :Yuqin Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Gene-encoded antibacterial peptides are multifunctional effector molecules and play an important role in host innate immunity. Upon stimulation, the mature active peptides are released from inactive precursors. LÄS MER