Sökning: "Human Dermal Fibroblasts"

Visar resultat 16 - 20 av 27 avhandlingar innehållade orden Human Dermal Fibroblasts.

  1. 16. The roles of microRNAs in skin wound healing

    Författare :Xi Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Skin is an essential biological barrier of the human body, and wound healing is the fundamental physiological process to keep its integrity. Chronic non-healing wounds are growing socioeconomic and health concerns, which longs for more understanding of their pathophysiology to discover effective treatments. LÄS MER

  3. 17. Non-coding RNAs and Extracellular Vesicles in Cutaneous Squamous Cell Carcinoma

    Författare :Chen Li; Andor Pivarcsi; Gareth Inman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cutaneous squamous cell carcinoma; microRNA; long non-coding RNA; extracellular vesicle;

    Sammanfattning : Cutaneous squamous cell carcinoma (cSCC) ranks among the most widespread malignancies with metastatic potential. Investigating the molecular mechanism of tumorigenesis will enhance our understanding of cSCC. Aberrant expression of non-coding RNAs has been extensively reported in human cancers. LÄS MER

  4. 18. Effect of Hyaluronan-activation of CD44 on Cell Signaling and Tumorigenesis

    Författare :Lingli Li; Paraskevi Heldin; Raija H. Tammi; Uppsala universitet; []
    Nyckelord :Biomedicine; Hyaluronan; CD44; growth factors; chemokines; tumorigenesis; wound healing; cell signaling; Biomedicin;

    Sammanfattning : Hyaluronan (HA), a structural component in the extracellular matrix (ECM), has been recognized as a signaling molecule. It is important during various biological activities such as embryogenesis, angiogenesis, wound healing and tumor progression. LÄS MER

  5. 19. Mechanisms Underlying the Specification of Definitive Hematopoiesis

    Författare :Rita Alves; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GATA2; mitotic bookmarking; HSC; transcription factors; reprogramming;

    Sammanfattning : Hematopoietic stem cells (HSCs) maintain blood through self-renewal and differentiation. Although HSC transplantation is the only cure for various blood disorders, generating and maintaining HSCs in vitro remains challenging, partly due to a limited understanding of the cellular and molecular mechanisms underlying human HSC ontogeny. LÄS MER

  7. 20. Nanocellulose for Biomedical Applications : Modification, Characterisation and Biocompatibility Studies

    Författare :Kai Hua; Natalia Ferraz; Maria Strømme; Albert Mihranyan; Pedro Granja; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Nanocellulose; nanofibrillated cellulose; Cladophora cellulose; biocompatibility; inflammation; surface modification; surface group density; surface topography; Engineering Science with specialization in Nanotechnology and Functional Materials; Teknisk fysik med inriktning mot nanoteknologi och funktionella material;

    Sammanfattning : In the past decade there has been increasing interest in exploring the use of nanocellulose in medicine. However, the influence of the physicochemical properties of nanocellulose on the material´s biocompatibility has not been fully investigated. LÄS MER