Sökning: "Homology Inference"

Visar resultat 6 - 8 av 8 avhandlingar innehållade orden Homology Inference.

  1. 6. Computational Problems in Modeling Evolution and Inferring Gene Families

    Författare :Mehmood Alam Khan; Lars Arvestad; Jens Lagergren; Christophe Dessimoz; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Evolution; Phylogenetics; Lateral Gene Transfer; Gene Families; Clustering; Datalogi; Computer Science;

    Sammanfattning : Over the last few decades, phylogenetics has emerged as a very promising field, facilitating a comparative framework to explain the genetic relationships among all the living organisms on earth. These genetic relationships are typically represented by a bifurcating phylogenetic tree — the tree of life. LÄS MER

  3. 7. Unlocking protein sequences : Advances in protein structure and ligand-binding site prediction

    Författare :Aditi Shenoy; Arne Elofsson; Geoffrey J Barton; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Sammanfattning : The protein sequence determines how it will fold into its unique three-dimensional structure. Once folded, proteins perform their functions by interacting with other proteins or molecules called ligands within the cell. Experimental determination of protein structure and function is tedious. LÄS MER

  4. 8. Analyses of protein evolution, function, and architecture

    Författare :Anna Henricson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Proteins can evolve over time in many different ways. An ancestral protein sequence inherited in different species will gradually undergo changes in primary sequence and sometimes in domain architecture. Some of these changes will affect its function, and evolutionary analyses can be used to predict function shift. LÄS MER