Sökning: "HLA class II antibodies"

Visar resultat 1 - 5 av 29 avhandlingar innehållade orden HLA class II antibodies.

  1. 1. HLA genetics in multiple sclerosis

    Författare :Jenny Link; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a chronic disease in which both genetic and environmental risk factors contribute to disease susceptibility. MS patients suffer from inflammatory lesions in the central nervous system which results in demyelination of nerve cells, reduced neuronal activity and finally neurodegeneration. LÄS MER

  3. 2. Polyglandular Autoimmune (PGA) Syndromes and associations to sarcoidosis

    Författare :Konstantinos I Papadopoulos; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiotensin converting enzyme ACE ; DQB1; DRB1; HLA; H K ATPase; antigliadin; autoantibodies; pernicious anaemia; coeliac disease; sarcoidosis; Hashimoto thyroiditis; Graves disease; autoimmune thyroid disease; Addison s disease; Polyglandular autoimmune PGA syndromes; autoimmunity; ACE gene polymorphism; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : Polyglandular Autoimmune (PGA) syndrome type II in idiopathic Addison's disease: In a retrospective study of idiopathic Ad-dison's disease (median age at diagnosis 32.5 years, range 8-62; median observation time 17 years, range 0.5-41), 50% met the criteria for PGA syndrome type II. In PGA syndrome type II, 73% had ATD and 41% had IDDM. LÄS MER

  4. 3. Alloimmunization during pregnancy with special emphasis on anti-D : Laboratory and clinical management

    Författare :Derek Filbey; Lennart Rydberg; Linköpings universitet; []
    Nyckelord :Alloimmunization in pregnancy; Anti-D; Haemolytic disease of the newborn HDN ; IAT-titration; AA-quantitation; Chemiluminescence test; Category D; HLA class II antibodies; MEDICINE; MEDICIN;

    Sammanfattning : The laboratory and clinical management of alloimmunized in pregnancy has been investigated according to a protocol currently in use in Örebro region. A 12 year epidemiological study showed the prevalence of alloimmunization to be 0.57% in this Swedish populationwith a 0. LÄS MER

  5. 4. HLA polymorphism : genomic typing and impact on unrelated stem cell transplantation

    Författare :Anna Aldener-Cannavá; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The HLA (Human Leukocyte Antigen) region is the most polymorphic in the human genome. The extended polymorphism contributes to the ability both of individuals and populations to combat diversity in the pathogens to which they are exposed. LÄS MER

  7. 5. Anti-citrulline immunity in rheumatoid arthritis : characterization of peptide-HLA interactions and CD4+ T cell responses

    Författare :Christina Gerstner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rheumatoid Arthritis (RA) is a complex, systemic autoimmune disorder characterized by chronic inflammation in small joints in hands and feet. It is a common disease that if untreated leads to joint destruction, disability, comorbidities and a reduced lifespan. LÄS MER