Sökning: "Caroline Gélabert"

Hittade 1 avhandling innehållade orden Caroline Gélabert.

1. 1. Micro-environmental control of tumor differentiation and invasiveness

   Författare :Caroline Gélabert; Aristidis Moustakas; Alexander Pietras; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; cell signaling; TGFβ; non-coding RNAs; metabolism;

   Sammanfattning : The transforming growth factor β (TGFβ) family participates in embryonic development and adult tissue homeostasis. In early stages of tumorigenesis, TGFβ promotes cell cycle arrest and apoptosis; however, in advanced malignancies, TGFβ promotes tumor cell migration and metastasis via the induction of epithelial-tomesenchymal transition (EMT). LÄS MER