Sökning: "Carbohydrate recognition"
Visar resultat 21 - 25 av 42 avhandlingar innehållade orden Carbohydrate recognition.
21. Galectin-8 specificity to cells: from broad outside to fine inside
Sammanfattning : Glycobiology is the world of sugars: how they are made, what they look like, and what they do. Despite the importance of glycan structures in life, knowledge has been hampered due to their inherent complexity. LÄS MER
22. Structural insights into glycoprotein transport and viral escape
Sammanfattning : The correct trafficking of proteins through the secretory pathway is essential for the maintenance of cellular functions. Increasing evidence suggests that at least for some glycoproteins, export from the endoplasmic reticulum (ER) is mediated by interaction with cargo receptors. LÄS MER
23. Development and Evaluation of Tools to Explore Posttranslational HexNAc-Tyrosine and Mucin-Type O-Glycosylation
Sammanfattning : Glycosylation is the most abundant form of post-translational modification (PTM). Recently, O-glycosylation attracted much attention in the glycoproteomic field due to its association with various diseases, such as pathogenic infections and cancer. LÄS MER
24. Functional properties of galectin-3. Beyond the sugar binding
Sammanfattning : Contemporary diseases like diabetes, asthma, atherosclerosis etc. are marked by chronic inflammation, often supported by the activity of different macrophages. Proteins from galectin family were found to contribute to disease pathophysiology. Therefore, there is an intensive interest in understanding different galectin functions. LÄS MER
25. Reading a glycocode - mechanism and function of galectin-glycan interactions
Sammanfattning : There is an intensive interest in characterising the structure and function of galectins, which is not surprising given their many important cellular functions and strong implications in human disease. Understanding the mechanisms involved in galectin functions will help to find selective and novel strategies for disease treatment and diagnosis. LÄS MER