Sökning: "CGH"

Visar resultat 26 - 30 av 76 avhandlingar innehållade ordet CGH.

  1. 26. Clinical and molecuar studies of papillary thyroid carcinoma : with an emphasis on prognostic factors

    Författare :Petra Kjellman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Papillary thyroid carcinoma; MIB-1; RET-proto-oncogene; RET PTC; CGH; prognosis;

    Sammanfattning : Thyroid cancer accounts for approximately 1% of all cancers reported. In Sweden 45/100, 000 inhabitants annually present with thyroid carcinoma. There are four different variants of thyroid carcinoma: papillary thyroid carcinoma (PTC), follicular thyroid carcinoma, medullary thyroid carcinoma and anaplastic thyroid carcinoma. LÄS MER

  3. 27. Molecular genetic aspects of renal cell carcinoma development

    Författare :Andrei Alimov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Kidney tumor; RCC; LOH; CGH; SKY; PTEN; chromosome 3p; chromosome 10q; chromosome 14q;

    Sammanfattning : Renal cell carcinoma (RCC) is the most common tumor of the renal parenchyma. The aim of this study was to further characterize known as well as new genetic abnormalities in a clinical material of RCC, as well as in established cell lines to gain more information about etiological and progression factors. LÄS MER

  4. 28. A functional genomics approach to study prostate disorders

    Författare :See-Tong Pang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Prostate cancer; BPH; androgen; DNA microarray; gene expression; CGH; SKY; oxidative stress.;

    Sammanfattning : Benign prostate hyperplasia (BPH) and prostate cancer (PCa) are the two most common prostatic disorders in elderly man. Currently, the causes of both diseases are still not clear. However, androgen is a well recognized risk factor for both diseases. LÄS MER

  5. 29. Genomic changes defining the progression of human colorectal and cervical tumors

    Författare :Kerstin Heselmeyer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :colorectal; cervical; anal neoplasias proliferation; DNA ploidy; p53 and p21WAF1 expression; HPV; CGH;

    Sammanfattning : Defining changes during the carcinogenesis and progression of tumors is a major way to obtain a better understanding of the mechanisms of cancer development. We therefore investigated the carcinogenesis process in the colon-rectum and in the uterine cervix by different cell chemical, immunohistochemical and cytogenetic methods. LÄS MER

  7. 30. Molecular genetic studies of human thyroid tumors

    Författare :Tony Frisk; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Follicular thyroid tumors; tumor progression; Cowden disease; PTEN; CGH; RET; medullary thyroid carcinoma; MEN 2; anaplastic carcinoma.;

    Sammanfattning : Tumors of the thyroid gland are common among the general population, but only a small proportion is malignant. The vast majority of thyroid tumors are benign, so called follicular adenomas. Sometimes subtypes such as atypical adenomas and adenomas with oxyphil, i.e. LÄS MER