Sökning: "CD25"

Visar resultat 16 - 20 av 75 avhandlingar innehållade ordet CD25.

  1. 16. On the regulation of immune responses to dietary and self antigens

    Författare :Susanne Lindgren; Göteborgs universitet; []
    Nyckelord :Tolerance; regulatory T cells; self antigens; oral tolerance; dietary antigens; intestinal epithelial cells; exosomes; Staphylococcus aureus enterotoxin A;

    Sammanfattning : Regulatory mechanisms are necessary to avoid the misdirected aggressive immune responses responsible for the pathology seen in autoimmunity and allergy. Thymic-derived CD4+CD25+ regulatory T cells are indispensible for this regulation. We investigated if CD4+CD25+ Treg prevents auto-reactive responses in adult peripheral blood and cord blood. LÄS MER

  3. 17. CNS-Targeted Cell Therapy for Multiple Sclerosis

    Författare :Moa Fransson; Angelica Loskog; Tomas Olsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CAR; Targeting; Suppressive cells; Foxp3; Tregs; Clinical immunology; Klinisk immunologi; Immunologi; Immunology;

    Sammanfattning : Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system (CNS). In the current thesis, we have preformed an immunological investigation of patients with MS and developed an immunosuppressive cell therapy that could be beneficial for these patients. LÄS MER

  4. 18. From natural to eximious : harnessing the power of natural killer cells against solid tumors

    Författare :Ziqing Chen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer heterogeneity, which enables clonal survival and treatment resistance, is shaped by active immune responses. Unchallenged results from clinical trials show the power of stimulating our immune system to attack tumor cells. Engineered T cells and checkpoint blockade are at the forefront of current immunotherapy strategies. LÄS MER

  5. 19. On immunotherapy against prostate cancer

    Författare :Kajsa Lundberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostate cancer (PC) is the most frequently diagnosed cancer in Swedish men, with an incidence of around 9000 cases per year, and the main cause of cancer related death. Standard treatment includes surgery, radiotherapy and hormonal therapy. LÄS MER

  7. 20. Immune profile from high-risk to onset of Type 1 diabetes

    Författare :Anna Rydén; Maria Faresjö; Johnny Ludvigsson; Malin Flodström-Tullberg; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Type 1 diabetes (T1D) is most often diagnosed early in life and is usually the result of an autoimmune attack on the insulin producing β-cells of the pancreas, leading to a lack of insulin secretion and life-long insulin treatment. The search for possible targets pin-pointing the β-cell destruction is a constant endeavour in the pursuit to prevent T1D onset. LÄS MER