Sökning: "Bronchoscopy"

Visar resultat 11 - 15 av 24 avhandlingar innehållade ordet Bronchoscopy.

  1. 11. Endotoxin-induced inflammation in healthy human airways

    Författare :Margaretha E. Smith; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LPS; neutrophils; bronchoalveolar lavage; human airways; innate immunity;

    Sammanfattning : The aim of this thesis was to investigate the innate immune response in healthy human airways in vivo after simulation of a Gram-negative infection. Intrabronchial exposure to the TLR4 agonist endotoxin was used as a model for the innate mechanisms in the immune response that are caused by cigarette smoke and by natural infection with Gram-negative bacteria. LÄS MER

  3. 12. Pulmonary manifestations in smoking-related diseases : clinical studies with emphasis on chronic obstructive pulmonary disease and rheumatoid arthritis

    Författare :Reza Karimi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Smoking is a risk factor for a number of diseases including chronic obstructive pulmonary disease (COPD) and rheumatoid arthritis (RA). Cigarette smoke initiates an inflammatory response which leads to structural changes in the airways and in the lung parenchyma. LÄS MER

  4. 13. Activation of epithelial signal transduction pathways, cytokine production and airway inflammation following diesel exhaust exposure

    Författare :Jamshid Pourazar; Thomas Sandström; Anders Blomberg; Anders Lindén; Umeå universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Adverse health effects of ambient air pollution are well recognised and include increased morbidity and mortality in respiratory and cardiovascular diseases. Diesel engines are major contributors to ambient particulate matter pollution and diesel particles have been shown to have strong toxicological and oxidative properties. LÄS MER

  5. 14. Molecular and epidemiological investigations of lung involvement in very early rheumatoid arthritis

    Författare :Guðrún Björk Reynisdóttir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rheumatoid arthritis (RA) is a systemic inflammatory joint disease with at least two distinct clinical phenotypes defined by the presence or absence of antibodies, i.e. rheumatoid factor (RF) and/or anti-­citrullinated protein antibodies (ACPAs). LÄS MER

  7. 15. Airway inflammation in "healthy" smokers. Relation to lung function and high resolution CT findings

    Författare :Ann Ekberg-Jansson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic obstructive pulmonary disease; smoking; bronchoalveolar lavage; bronchial biopsies; cytokines; lymphocytes; computed tomography; lung function; respiratory symptoms;

    Sammanfattning : The aim of the present study was to characterize the inflammatory pattern in "healthy"smokers and relate it to lung function, high resolution computed tomography (HRCT) findings and respiratory symptoms in order to identify smokers at risk to develop COPD. Subjects were recruited from a population study "Men born 1933 in Göteborg". LÄS MER