Sökning: "Bone Morphogenetic Protein BMP"

Visar resultat 16 - 20 av 37 avhandlingar innehållade orden Bone Morphogenetic Protein BMP.

  1. 16. Signaling mechanisms underlying neural stem cell differentiation. Implications of BMPs, retinoids, and MAP kinases

    Författare :Roland Faigle; Göteborgs universitet; []
    Nyckelord :neural stem cells; differentiation; BMP; ASK1; p38 MAP kinase; CNTF; retinoic acid;

    Sammanfattning : Introduction: Neural stem cells are proliferating cells, derived from the nervous system with the ability to give rise to neurons, astrocytes, and oligodendrocytes. The molecular events and signaling pathways regulating neural stem cell differentiation are largely unknown. LÄS MER

  3. 17. Specification of the lens and olfactory placodes and dorsoventral patterning of the telencephalon

    Författare :My Sjödal; Juha Partanen; Umeå universitet; []
    Nyckelord :telencephalon; olfactory; lens; BMP; RA; FGF; Wnt; development; placode; gradient; chick; nervous system; dorsoventral; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences;

    Sammanfattning : The vertebrate nervous system is a highly complex and intriguing structure with diverse functions. To understand the functional nervous system, we first have to be aware of how it is assembled during development. LÄS MER

  4. 18. Bone Morphogenetic Protein Receptors in the Nervous System: Neurotrophic Functions with Emphasis on Catecholaminergic Neurons

    Författare :Henrik Bengtsson; Åke Seiger; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; medicinsk utvecklings- och neurobiologi;

    Sammanfattning : Members of the transforming growth factor-β (TGF-β) superfamily exhibit a range of effects on a host of different cell types. They signal through heteromeric complexes of serine/threonine kinase receptors of type I and type II. LÄS MER

  5. 19. Transforming growth factor-ß. Signal regulation in health and disease

    Författare :Urban Molander; Göteborgs universitet; []
    Nyckelord :TGF-b; BMP; Smad; signal transduction; LDL; skin tumour; mesangial;

    Sammanfattning : TGF-b superfamily members have been shown to play a pivotal role in multicellular organisms. Knowledge about signal transduction pathways is important in order to understand and cure diseases like cancer where TGF-b´s growth inhibitory signal often are disenabled via mutated or absent signalling components. LÄS MER

  7. 20. Directing stem cells and progenitors towards neuronal differentiation - implications for experimental therapies for Parkinson's disease

    Författare :Anke Brederlau; Göteborgs universitet; []
    Nyckelord :stem cells; Parkinson s disease; progenitors; BMP; ASK1; dopamine;

    Sammanfattning : The insight that stem- and progenitor-cells contribute to replacement of nerve cells in the adult central nervous system is the basis of modern therapies for structural brain repair. Their goal is to protect, support and stimulate endogenous stem cells in areas affected by disease and to replace lost cells by transplanting in vitro generated, tailored nerve cells. LÄS MER