Avancerad sökning

Hittade 2 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Design and stereoselective syntheses of Phe-Phe dipeptidomimetics

   Författare :Annika Jenmalm Jensen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Organic Pharmaceutical Chemistry; organisk farmaceutisk kemi;

   Sammanfattning : Several stereochemically well characterized Phe-Phe dipeptidomimetics have been designed and synthesized. The Phe-Phe vinyl isostere was used as a key intermediate. The synthesized series of mimetics includes two isomeric epoxides, four 1,2-dihydroxyethylene isomers, two isomeric allylic alcohols and two isomeric allylic fluorides. LÄS MER

3. 2. Characterizing phenotypes of Mycobacterium tuberculosis and exploring anti-mycobacterial compounds through high content screening

   Författare :Sadaf Kalsum; Maria Lerm; Thomas Lundbäck; Annika Jenmalm; Lena Serrander; Priscille Bordin; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Tuberculosis (TB), an airborne disease and one of the top 10 causes of death globally, is caused by Mycobacterium tuberculosis (Mtb). Current standard therapy for TB treatment includes multiple drugs for a period of at least 6 months. LÄS MER