Sökning: "Acute myeloid leukaemia"

Visar resultat 11 - 15 av 20 avhandlingar innehållade orden Acute myeloid leukaemia.

  1. 11. Botad - till vilket pris? : en studie över livskvalitet och kostnad vid konventionell behandling av akut myeloisk leukemi = [Cured - at what price?] : [a study on quality of life and costs in conventional treatment of acute myeloid leukaemia]

    Författare :Ann Marie Stalfelt; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 12. Leukaemic relapse after allogeneic haematopoietic stem cell transplantation and the use of the graft-versus-leukaemia effect

    Författare :Stefan Carlens; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :haematopoietic stem cell transplantation; GVHD; GVL; DLI; T-cell culture; retroviral transduction; NK-cell culture;

    Sammanfattning : Survival after allogeneic haematopoietic stem cell transplantation (HSCT) has improved over the last decades due to improvements in immunosuppressive regimens and supportive care. Today the major risk of treatment failure is recurrent leukaemia, a risk which has stayed relatively constant over the years. LÄS MER

  4. 13. Indicators of apoptosis and proliferation in haematological malignancies : with special reference to drug resistance and prognosis

    Författare :Barbara MacNamara; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acute Myeloid Leukaemia; Non-Hodgkin s Lymphoma Drug Resistance; Predictive Factor; International Prognostic Index; Apoptosis; Proliferation; Telomerase; BCL-2; BAX; p53;

    Sammanfattning : Successful treatment of acute myeloid leukaemia (AML) and high-grade non-Hodgkin's lymphoma (HG- NHL) is hampered by development of drug resistance. A better understanding of mechanisms responsible for drug resistance and the identification of factors that predict response to therapy is essential to improve treatment. LÄS MER

  5. 14. DNA-dependent protein kinase in normal and malignant cells : with special reference to anti-tumour agent sensitivity

    Författare :Åsa Holgersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DNA-PK; lymphoid maturation; lymphocytic leukaemia; radiation sensitivity; drug sensitivity; drug resistance; sensitisation.;

    Sammanfattning : The DNA-dependent protein kinase (DNA-PK) is a DNA double strand break (DSB) repair enzyme, essential for the cellular response to DNA damaging agents. DNA-PK is also of importance for lymphoid development, since it includes two processes, V(D)J recombination and lg switch recombination, during which DSBs are naturally occurring events. LÄS MER

  7. 15. Risk factors for haematological malignancies : immune-mediated diseases, body mass index and magnetic fields

    Författare :Karin Söderberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Leukaemia; lymphoma; myeloma; risk factors; allergic conditions; asthma; autoimmune diseases; body mass index; electromagnetic fields; epidemiology;

    Sammanfattning : Haematological malignancies constitute approximately 7% of all cancer cases in Sweden, and leukaemia is in fact the most common malignancy among children. The few established risk factors, such as ionising radiation and immunodeficiency, only explain a small number of the cases. LÄS MER