Sökning: "11q."

Visar resultat 6 - 10 av 26 avhandlingar innehållade ordet 11q..

1. 6. Array based genetic profiling of chronic lymphocytic leukemia

   Författare :Rebeqa Gunnarsson; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prognostic markers; copy-number neutral loss of heterozygosity; copy-number aberrations; chronic lymphocytic leukemia; genomic microarrays; clonal evolution; stereotyped B-cell receptors;

   Sammanfattning : Although no common genetic defect has been described in chronic lymphocytic leukemia (CLL), recurrent genomic aberrations (i.e. deletions of chromosome 11q, 13q, 17p and trisomy 12) are important for prognostication. Deletion of 13q as single aberration is associated with the best prognosis, whereas del(11q) and del(17p) predict a poor outcome. LÄS MER

3. 7. Molecular characterization of neuroblastoma tumors - a basis for personalized medicine

   Författare :Hanna Kryh; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; Cancer; Tumor; SNP-array; Micro array; DNA copy number;

   Sammanfattning : Neuroblastoma is a very heterogeneous tumor, with a clinical course ranging from spontaneous regression to aggressive tumor growth. A proper stratification of the patients into different risk groups is therefore important in order to provide the most suitable treatment for each patient. LÄS MER

4. 8. Clinical prognostic markers in chronic lymphocytic leukemia

   Författare :Stefan Norin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of mature B lymphocytes in blood, bone marrow and lymphoid tissues. The clinical course for the individual patient is still unpredictable despite decades of research on prognostic markers and staging systems. LÄS MER

5. 9. Investigation of genetic factors involved in colorectal cancer predisposition

   Författare :Tatjana Djureinovic; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :colorectal cancer CRC ; hereditary colorectal cancer HCRC ; two-close relatives TCR ; linkage analysis; case-control;

   Sammanfattning : Colorectal cancer (CRC) is one of the leading causes of cancer-related death in the western world. Several hereditary CRC predisposing syndromes have been described and their genetic component has been elucidated. Taken together, these syndromes account for at most 5% of all CRC cases. LÄS MER

7. 10. Vitamin D and its receptor in parathyroid tumors

   Författare :Pamela Correa; Martin Bäckdahl; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; hyperparathyroidism; loss of heterozygoisty; vitamin D; vitamin D receptor; polymorphism; hydroxylase; genetics; tumorigenesis; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

   Sammanfattning : Correa, P. 2002. Vitamin D and its receptor in parathyroid tumors. Acta Universitatis Upsaliensis. LÄS MER