Sökning: "inner ear immunology"

Hittade 3 avhandlingar innehållade orden inner ear immunology.

  1. 1. The Round Window Membrane - Gateway to the Cochlea : A Morphological and Electrophysiological study

    Författare :Leif Nordang; Sten Hellström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Otorhinolaryngology; round window membrane; pseudomonas exotoxin; auditory brainstem response; hearing loss; endolymphatic sac; inner ear immunology; glutamate; nitric oxide inhibitor; glucocorticoid.; Otorhinolaryngologi; Otorhinolaryngology; Otorhinolaryngologi; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

    Sammanfattning : Topical treatment of several inner ear diseases through the round window membrane (RWM) might be feasible in the near future. Bacteria toxins, ototoxic drugs and noise trauma seem to harm the inner ear by a common pathway which involves, excessive outflow of the afferent neurotransmitter glutamate and formation of nitric oxide (NO), which can severely damage cells/nerve endings and lead to cell death. LÄS MER

  3. 2. Ear and hearing problems in Turner syndrome

    Författare :Annika Elmqvist Stenberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Turner syndrome; tympanic membrane pathology; hearing loss; otitis media; estrogen receptors; presbyacusis; immunology; mouse; rat; human; cochlea; psychosocial; audiometric testing.;

    Sammanfattning : Turner Syndrome is a common chromosomal disorder and affects approximately one in every 2000 newborn girl. The syndrome is defined as a total (45,X) or partial loss of the second sex chromosome in combination with the typical characteristic features, which are short stature (less than 150 cm), absent estrogen production due to ovarian dysgenesis, with failure to enter puberty spontaneously and infertility. LÄS MER

  4. 3. Complement aberrations and autoantibodies to complement proteins in relation to disease mechanisms

    Författare :Lillemor Melander Skattum; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C3 nephritic factors; GM allotypes; C1q autoantibodies; serum bactericidal activity; Neisseria meningitidis; idiopathic sudden hearing loss; complement; Acute poststreptococcal glomerulonephritis;

    Sammanfattning : The complement system, a part of the innate immune system with several links to the adaptive immune system, plays an important role in the pathogenesis of many diseases. The purpose of this thesis was to document and clarify some of these mechanisms. The thesis is based on four papers (I-IV). LÄS MER