Sökning: "Urban Lendahl"

Hittade 4 avhandlingar innehållade orden Urban Lendahl.

  1. 1. TRAF6 stimulates TGFβ-induced oncogenic signal transduction in cancer cells

    Författare :Shyam Kumar Gudey; Marene Landström; Urban Lendahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; c-Jun; invasion; non-Smad; Notch; NICD; oncogenesis; presenilin1; PKCζ; prostate cancer; p21; p38; p300; Snail1; TGFβ; TβRI; TACE; TRAF6; ubiquitination; TGFbeta signal transduction; Pathology; patologi;

    Sammanfattning : Prostate cancer is one of the leading causes of cancer-related deaths in men worldwide, with 10,000 new cases/year diagnosed in Sweden. In this context, there is an urgent need to identify new biomarkers to detect prostate cancer at an initial stage for earlier treatment intervention. LÄS MER

  3. 2. The Role of the SHB Adapter Protein in Cell Differentiation and Development

    Författare :Vitezslav Kriz; Michael Welsh; Urban Lendahl; Uppsala universitet; []
    Nyckelord :Cell biology; SHB; transgene; ES cells; cavitation; knockout; mouse; vasculogenesis; hematopoiesis; endoderm; mesoderm; malformation; Cellbiologi;

    Sammanfattning : The present study was conducted in order to assess a role of the SH2 domain-containing adapter protein SHB in development and cell differentiation.Embryonic stem (ES) cells overexpressing SHB and SHB with an inactive SH2 domain (R522K-SHB) were obtained. LÄS MER

  4. 3. Genetic and Functional Analysis of Cell Adhesion in Muscle

    Författare :Wen Kuang; Urban Lendahl; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Zoological Developmental Biology; zoologisk utvecklingsbiologi;

    Sammanfattning : Skeletal muscle is one of the most abundant tissues in the body, and its main function is to generate the force for movement. The mature muscle cell is a giant, elongated, multinucleated cell surrounded by a specialized, extracellular matrix (ECM), the basement membrane (BM). LÄS MER

  5. 4. Molecular and functional anatomy of the mouse olfactory epithelium

    Författare :Viktoria Vedin; Anna Berghard; Urban Lendahl; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; olfactory epithelium; odorant receptor; zone; odorant; gene expression; cell specification; c-Fos; dichlobenil; olfactometry; proliferation; Molecular biology; Molekylärbiologi;

    Sammanfattning : The olfactory system is important for social behaviors, feeding and avoiding predators. Detection of odorous molecules is made by odorant receptors on specialized sensory neurons in the olfactory epithelial sheet. LÄS MER