Sökning: "Diclofenac"

Visar resultat 1 - 5 av 44 avhandlingar innehållade ordet Diclofenac.

  1. 1. Renal dysfunction in orthopaedic surgery - with special reference to drug effects in the elderly

    Författare :Görel Nergelius; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; orthopaedics; Surgery; protein HC; IgG; albumin; pharmacokinetics; diclofenac; clearance; elderly; penicillin; isoxazolyl; tubular; glomerular; arthroplasty; exercise; traumatology; Kirurgi; ortopedi; traumatologi; Anaesthesiology; intensive care; Anestesiologi; intensivvård;

    Sammanfattning : Total hip replacement (THR) is a common procedure, generally performed in elderly persons. Previous studies indicated that the use of isoxazolyl penicillins could induce a transient post-operative renal dysfunction in these patients. LÄS MER

  3. 2. Endothelium-Dependent Vasodilation and Oxidative Stress in Chronic Renal Failure

    Författare :Margus Annuk; Ola Samuelson; Uppsala universitet; []
    Nyckelord :Medical sciences; endothelium; oxidative stress; chronic renal failure; L-arginine; diclofenac; erythropoietin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Internal Medicine; invärtesmedicin;

    Sammanfattning : Cardiovascular disease (CVD) is the major cause of death in patients with chronic renal failure (CRF). Endothelial function and oxidative stress (OS) have previously been shown to be important in the pathogenesis of CVD. In this thesis, the endothelium-dependent vasodilatation (EDV) and OS were investigated in the patients with CRF. LÄS MER

  4. 3. Wastewater treatment from pharmaceutical substances with filamentous fungi

    Författare :Brigita Dalecka; Gunaratna Kuttuva Rajarao; Talis Juhna; Paul Van der Wielen; Lima Nelson; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Filamentous fungi; municipal wastewater; pharmaceutical substances; fungal fluidized bed pelleted bioreactor; nutrients; diclofenac; ketoprofen; Trametes versicolor; Aspergillus luchuensis; Filamentösa svampar; kommunalt avloppsvatten; läkemedelsrester; bioreaktor; näringsämnen; diklofenak; ketoprofen; Trametes versicolor; Aspergillus luchuensis; Mikroskopiskās sēnes; sadzīves notekūdeņi; farmaceitiskās vielas; mikroskopisko sēņu bioreaktors; diklofenaks; ketoprofens; Trametes versicolor; Aspergillus luchuensis; Bioteknologi; Biotechnology;

    Sammanfattning : The ever-increasing concern about the widespread occurrence of pharmaceutical substances in the aquatic environment has been recognized as an emerging environmental issue as it can cause undesirable effects on the ecosystem and human health. The current wastewater treatment methods are not designed to treat municipal wastewater from the contamination of various pharmaceutical substances. LÄS MER

  5. 4. Cytochrome P450 2C9 polymorphism : interindividual differences in drug metabolism and phenotyping methodology

    Författare :Umit Yasar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :CYP2C9 polymorphism; phenotyping; genotyping; diclofenac; losartan;

    Sammanfattning : Cytochrome P450 2C9 (CYP2C9) is one of the most important drug metabolizing enzymes in human liver. It catalyses the metabolism of a wide range of different drugs such as S-warfarin, acenocoumarol, losartan, irbesartan, phenytoin, sulphamethoxazole, tolbutamide, glipizide and numerous non-steroidal antiinflammatory drugs. LÄS MER

  7. 5. Molecular Mechanisms of Graves' Ophthalmopathy. A focus on smoking and radioiodine

    Författare :Bushra Shahida; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Graves’ disease. Graves’ ophthalmopathy; radioiodine; inflammation; adipogenesis; IL-1ß; IL-6; PTGS2 COX2; PGE2; CTLA-4; B lymphocytes; T lymphocytes; Simvastatin; Diclofenac; SNP; gene expression; IGF-1;

    Sammanfattning : Graves’ disease (GD) is an autoimmune disease characterized by hyperthyroidism and is caused by an interplayof genetic and environmental factors. One-third of patients with GD develop Graves’ ophthalmopathy (GO). Keyprocesses in the pathogenesis of GO are inflammation and adipogenesis in orbital tissue. LÄS MER