Sökning: "Click reaction"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden Click reaction.

  1. 1. Functional Dendritic Materials using Click Chemistry : Synthesis, Characterizations and Applications

    Författare :Per Antoni; Anders Hult; Michael Malkoch; Stefan Hecht; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Dendrimer; Dendron; Dendritic; Hyperbranched; Click; Chemistry; CuAAc; One-Pot; Multi-functional; Simultaneous; Honeycomb; Isoporous; MALDI; NMR; GPC; TGA; DSC; Polymer chemistry; Polymerkemi;

    Sammanfattning : Förfrågan efter nya och mer avancerade applikationer är en pågående process vilket leder till en konstant utveckling av nya material. För att förstå relationen mellan en applikations egenskaper och dess sammansättning krävs full förståelse och kontroll över materialets uppbyggnad. LÄS MER

  3. 2. One-click away from higher contrast : Improvements to peripheral clearance for same-day immunoPET in Alzheimer’s disease

    Författare :Eva Schlein; Dag Sehlin; Jordi Llop Roig; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease AD ; bispecific antibody; Amyloid-β Aβ ; Receptor mediated transcytosis RMT ; Neonatal Fc receptor FcRn ; Blood-brain barrier BBB ; Inverse electron demand Diels−Alder reaction IEDDA; pre-targeting; tetrazine; bio-orthogonal; Fluorine-18; clearing agent;

    Sammanfattning : The brain is a challenging target for antibody-based positron emission tomography (immunoPET) to image amyloid-beta (Aβ). Antibodies detect pathology with high sensitivity, but due to their size and biological half-life, they cause a high background radiation, if radiolabelled. LÄS MER

  4. 3. Perfluroaryl azides : Reactivities, Unique Reactions and their Applications in the Synthesis of Theranostic Agents

    Författare :Sheng Xie; Mingdi Yan; Olof Ramström; Stefan Bräse; KTH; []
    Nyckelord :Click Chemistry; Dipolar Cycloaddition; Enamine; Triazoline; Amidine; Aggregation-induced emission; pure nanodrugs; aryl amide; thioacid azide reaction; nucleophilic aromatic substitution; azide-masked fluorophore; nitrene insertion; Kemi; Chemistry;

    Sammanfattning : The work centersaround perfluoroaryl azides (PFAAs), and theirability to undergo certain fast and robusttransformations. The chemistry was furtherappliedfor biomedical applications.The first section focuses on the azide-aldehyde-amine cycloaddition using PFAAs. LÄS MER

  5. 4. Bottom-up Fabrication of Functional DNA Nanostructures

    Författare :Erik Lundberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; click chemistry; gel electrophoresis; self-assembly; cross-linking; lipid membrane; fixation; linear dichroism; nanotechnology; spectroscopy; fret; dna; triplex recognition;

    Sammanfattning : This thesis demonstrates bottom-up fabrication of a fully addressable non-repetitive network on the nanometer scale, assembled by synthetic DNA molecules. Each side constitutes a unique sequence of 10 bases, i.e. 3. LÄS MER

  7. 5. Fabrication of Functional Molecularly Imprinted Materials using Nanoparticle Building Blocks

    Författare :Changgang Xu; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecularly imprinted polymers; magnetic susceptibility; click chemistry; PFPA; Pickering emulsion; chemical conjugation;

    Sammanfattning : Molecularly imprinted polymers (MIPs) have attracted great interest in many applications including bioseparation, chemical sensing, catalysis, drug delivery, etc. Recently, molecularly imprinted nanoparticles have become accessible due to a number of synthetic methods that have been developed. LÄS MER