Sökning: "Anders Hult"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden Anders Hult.

1. 1. Thiol-Ene CHemistry and Dopa-Functional Materials towards Biomedical Applications

   Författare :Kristina Olofsson; Anders Hult; Michael Malkoch; Anders Daugaard; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Thiol-ene chemistry; DOPA; biomedical; UV; Fiber- och polymervetenskap; Fibre and Polymer Science;

   Sammanfattning : Thiol-ene chemistry is versatile and efficient and can be used as a powerful tool in polymer synthesis. In this thesis, the concept of thiol-ene chemistry has been central, where it has been explored as a tool for the synthesis of well-defined hydrogels and dopa-functional materials towards biomedical applications; such as hydrogels, primers for adhesive fixation of bone fractures, self-healing gels, and micelles for drug-delivery. LÄS MER

3. 2. Enzyme selectivity as a tool in analytical chemistry

   Författare :Anders Hamberg; Karl Hult; Harry Brumer; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; substrate specificity; competing substrates; enantiomeric excess analysis; library screening; ladder sequencing; carboxypeptidase Y; 2-pyridylmethylamine; MALDI; Candia antarctica lipase B; pig liver esterase; horse liver alcohol dehydrogenase; acylated cyanohydrins; Biochemistry; Biokemi;

   Sammanfattning : Enzymes are useful tools as specific analytical reagents. Two different analysis methods were developed for use in the separate fields of protein science and organic synthesis. Both methods rely on the substrate specificity of enzymes. Enzyme catalysis and substrate specificity is described and put in context with each of the two developed methods. LÄS MER

4. 3. Serine Hydrolase Selectivity : Kinetics and applications in organic and analytical chemistry

   Författare :Anders Hamberg; Karl Hult; Dick Janssen; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida antarctica lipase B; monoacylation of diols; kinetic resolution; thermodynamics in enzyme catalysis; enzyme engineering; Biochemistry; Biokemi;

   Sammanfattning : The substrate selectivities for different serine hydrolases were utilized in various applications, presented in papers I-VI. The articles are discussed in the thesis in view of the kinetics of the enzyme catalysis involved. LÄS MER

5. 4. Rational redesign of Candida antarctica lipase B

   Författare :Anders Magnusson; Karl Hult; Bernhard Hauer; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Candida antarctica lipase B; rational redesign; secondary alcohols; substrate-assisted catalysis; S-selective; entropy; aldolase; stereospecificity pocket; oxyanion hole.; Biokemi; Biochemistry; Biokemi;

   Sammanfattning : This thesis describes the use of rational redesign to modify the properties of the enzyme Candida antarctica lipase B. Through carefully selected single-point mutations, we were able to introduce substrate-assisted catalysis and to alter the reaction specificity. LÄS MER

7. 5. Nonlinear phonocardiographic Signal Processing

   Författare :Christer Ahlström; Per Ask; Anders Johansson; Peter Hult; Pablo Laguna; Linköpings universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Signal analysis methods; computerized cardiac auscultation system; phonocardiographic PCG signal; mitral insufficiency MI ; time- and cost-saving; Medical engineering; Medicinsk teknik;

   Sammanfattning : The aim of this thesis work has been to develop signal analysis methods for a computerized cardiac auscultation system, the intelligent stethoscope. In particular, the work focuses on classification and interpretation of features derived from the phonocardiographic (PCG) signal by using advanced signal processing techniques. LÄS MER