Sökning: "virus genome structure"

Visar resultat 26 - 30 av 34 avhandlingar innehållade orden virus genome structure.

  1. 26. Concepts in DNA immunization overcoming viral diversity and enhancing plasmid immunogenicity

    Författare :Erik Rollman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; DNA-vaccine; gp 160; GM-CSF; HPV 16 L OBS I; MuLV; prime-boost;

    Sammanfattning : On April 23, 1984, the prominent scientist Robert Gallo held a historical press conference at the Department of Health and Human Services, Washington D.C., USA. He announced that his laboratory at the National Institutes of Health had over the last months isolated a retrovirus named Human T-cell Leukemia Virus type III (HTLV-III). LÄS MER

  3. 27. Alphavirus-host interactions : how to unravel the proviral activity of G3BP

    Författare :Benjamin Götte; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The genus Alphavirus belongs to the virus family Togaviridiae, a group of arthropod-borne enveloped RNA viruses with single-stranded, positive-sense genome. Members of this genus can be found worldwide and are geographically distinguished into Old World and New World alphaviruses. LÄS MER

  4. 28. Genetic aspects of HIV-1 evolution and transmission

    Författare :Irina Maljkovic Berry; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : HIV-1 is one of the fastest evolving organisms known to man. Its rate of evolution is approximately one million times faster than that of higher organisms such as ourselves, meaning that the amount of changes within the HIV-1 genome in just one year corresponds to the amount of changes within the human genome in one million years. LÄS MER

  5. 29. Transcription factor effects on chromatin organisation and gene regulation

    Författare :Per-Henrik Holmqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Chromatin; enhanceosome; MMTV; GR; NF1; Oct1; FoxA;

    Sammanfattning : The intranuclear DNA of all eukaryotic cells is packed into chromatin, generating a repressive environment for the genome. Remodelling of the local chromatin structure is a vital process that allows access to the obscured DNA sequence and may induce the expression of specific genes. LÄS MER

  7. 30. Characterization of transcription of genomic regions harboring HERV-W elements

    Författare :Fang Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human endogenous retroviruses (HERV) comprise 8% of the human genome and can be classified into at least 31 families. A typical HERV provirus consists of internal gag, pol and env genes, flanked by two long terminal repeats (LTRs). HERV are by nature repetitive and have with few notable exceptions lost their protein-coding capacity. LÄS MER