Sökning: "strukturbiologi"

Visar resultat 41 - 45 av 264 avhandlingar innehållade ordet strukturbiologi.

  1. 41. Integrative structural biology of protein fibers: Spider silk and beta-lactoglobulin nanofibrils

    Författare :Danilo Hirabae De Oliveira; My Hedhammar; Christofer Lendel; Martin Humenik; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Spider Silk; Spidroin; fiber protein structure; amyloid-like fibers; Beta-lactoglobulin; Spindel silke; Spidroin; fiberproteinstruktur; amyloidliknande fibrer; Betalaktoglobulin; Biotechnology; Bioteknologi;

    Sammanfattning : Proteins found in nature offer a vast range of exceptional materials, including high-performancebiopolymers such as spider silks and whey protein nanofibrils. Fibrous proteins possess immensepotential for developing novel materials suited for various applications, such as medicalbiomaterials or industrial products. LÄS MER

  2. 42. Symbiotic and pathogenic factors in plant-microbe interaction: Structural basis of C-glycoside metabolism and lipoprotein transport in bacteria

    Författare :Valentina Furlanetto; Christina Divne; Mats Sandgren; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Plant-Bacteria Interaction; Symbiotic Communication; C-Glycosylated Compounds; Enzymatic Deglycosylation; Pathogenic Interactions; Lipoprotein Localization; Lol System; Biotechnology; Bioteknologi;

    Sammanfattning : The communication between plants and bacteria involves a complex chemical signaling network that mediates responses to various biotic and abiotic stresses, as well as establishing symbiotic relationships between different organisms.The first part of the thesis focuses on a mechanism for symbiotic communication between plants and bacteria and more specifically on how C-glycosylated aromatic polyketide compounds produced by plants can be used as a mechanism for plants to communicate with beneficial bacteria. LÄS MER

  3. 43. Generation and exploitation of proton motive force: Biochemical and structural analysis of three bacterial integral membrane proteins

    Författare :Pontus Emanuel Gourdon; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; X-ray crystallography; AcrB; structure; proteorhodopsin; multi-drug resistance; transhydrogenase; membrane proteins; proton motive force;

    Sammanfattning : Proton motive force, a necessity for all living cells, is generated and exploited by asignificant number of membrane-bound enzymes and transporters. The focus of thisthesis was to understand the physiological relevance, structure and mechanism of threesuch bacterial enzymes: proteorhodopsin; transhydrogenase; and AcrB. LÄS MER

  4. 44. Structural basis for metalloprotein catalysis : Characterization of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase PgsA1 and Bacillus anthracis ribonucleotide reductase R2

    Författare :Kristīne Grāve; Martin Högbom; Susanna Törnroth-Horsefield; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Sammanfattning : About a third of all proteins need to associate with a particular metal ion or metallo-inorganic cofactor to function. This interplay expands the catalytic repertoire of enzymes and reflects the adaption of these catalytic macromolecules to the environments they have evolved in. LÄS MER

  5. 45. Structural and functional studies of proteins of medical relevance : Protein-ligand complexes in cancer and novel structural folds in bacteria

    Författare :Robert Gustafsson; Pål Stenmark; Pavlína Řezáčová; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; X-ray crystallography; Cancer; MTH1; oxidised nucleotides; MTHFD2; nucleotide metabolism; one-carbon metabolism; Botulism; Botulinum neurotoxin; OrfX; OrfX gene cluster; Biochemistry; biokemi;

    Sammanfattning : X-ray crystallography is a tool for determining the structures of proteins and protein-ligand complexes. In this thesis the method has been employed to study several proteins of medical relevance.Cancer is a terrible disease, severely impacting those affected, as well as their family and friends. LÄS MER