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1. 1. Regulation of Injury Induced Schwann Cell Proliferation Schwann Cell Proliferation

   Författare :Åsa Fex Svenningsen; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; estrogen; signal transduction; insulin like growth-factors; Schwann cell; peripheral; nerve regeneration; Djurfysiologi; Animal physiology; progesterone;

   Sammanfattning : The purpose of this study was to investigate injury induced proliferation of Schwann cells with emphasis of the effects of the insulin-like growth factors (IGF-I and IGF-II) and the sex hormones progesterone and estrogen. Proliferation, measured as [3H] thymidine incorporation, was studied in cultured segments of the rat sciatic nerve or through the use of the thymidine analogue bromo- deoxy-uridine (BrdU) in combination with immunocytochemistry. LÄS MER