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Visar resultat 21 - 25 av 134 avhandlingar som matchar ovanstående sökkriterier.

  1. 21. Genetic association studies in allergic rhinitis

    Författare :Daniel Carlberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Allergic rhinitis (AR) is a global health problem that causes major disability worldwide. Nasal obstruction, secretion and itching are characterizing features of the disease. The development and severity of AR are determined by a complex interaction between environmental and genetic factors and the heritability for AR has been estimated to be high. LÄS MER

  3. 22. Systems Biology Based Approaches to Identify Biomarkers in Seasonal Allergic Rhinitis

    Författare :Hui Wang; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucocorticoids; Seasonal allergic rhinitis; Biomarkers; Gene expression microarray analysis; Proteomics; Multivariate analysis; Pathway analysis;

    Sammanfattning : Glucocorticoids (GC) are the most effective anti-inflammatory treatment for seasonal allergic rhinitis (SAR). However, a few patients with SAR show poor response to GC treatment. Hence, there is a clinical need to find biomarkers to predict and monitor treatment response. LÄS MER

  4. 23. Symptoms and aspects on eosinophil activity in allergic rhinitis

    Författare :Cecilia Ahlström-Emanuelsson; Lund näs- och halssjukdomar Öron-; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Allergic rhinitis is a major atopic disease. Even if much is known about the pathophysiology of this condition, and despite the fact that good treatments are available, there is a need for new treatment options, particularly for such aiming at new targets and reduced side effects. LÄS MER

  5. 24. Allergic rhinitis and intralymphatic vaccination : immune response and tolerance

    Författare :Eric Hjalmarsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The overall goal of this thesis was to study novel immunological mechanisms for the development of pollen-induced allergic rhinitis (AR) and to evaluate the clinical response in combination with immunological changes in AR patients treated with intralymphatic immunotherapy (ILIT). In paper I, an increased fraction of neutrophils were detected in the nasal mucosa of AR patients compared with healthy controls. LÄS MER

  7. 25. Innate defense mechanisms of the nasal airway

    Författare :Henrik Widegren; Lund näs- och halssjukdomar Öron-; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; Leukotriene B4; CC10; TNF-alpha; innate immunity; allergic rhinitis; Airway inflammation;

    Sammanfattning : Allergic and infectious rhinitis are prevalent conditions that besides a direct morbidity also causes exacerbations of asthma and chronic obstructive pulmonary disease. The immune mechanisms associated with various forms of rhinitis are not fully understood. LÄS MER