Sökning: "Gene expression microarray analysis"

Visar resultat 1 - 5 av 240 avhandlingar innehållade orden Gene expression microarray analysis.

  1. 1. Microarray Based Gene Expression Analysis in Cancer Research

    Författare :Cecilia Laurell; Joakim Lundberg; Peter Nilsson; Karin Dahlman-Wright; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adrenocortical tumour; apoptosis; cancer; classification; gene expression; microarray; p53; RNA amplification; Molecular biology; Molekylärbiologi;

    Sammanfattning : Biotechnological inventions during the 20th century have resulted in a wide range of approaches for explorations in the functional genomics field. Microarray technology is one of the recent advances which have provided us with snapshots of which genes are expressed in cells of various tissues and diseases. LÄS MER

  3. 2. Statistical analysis of gene expression data

    Författare :Erik Kristiansson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gene expression; DNA microarrays; linear models; empirical Bayes; quality control; gene regulation; categorical data analysis; logistic regression; heavy metal stress; ecotoxicology; gene expression;

    Sammanfattning : Microarray technology has become one of the most important tools for genome-wide mRNA measurements. The technique has been successfully applied to many areas in modern biology including cancer research, identification of drug targets, and categorization of genes involved in the cell cycle. LÄS MER

  4. 3. Contributions to Statistical Analysis of Gene Expression Data

    Författare :Anders Sjögren; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA microarray; differential expression; gene regulation; variance stabilising transformation; permutation; reference gene; housekeeping gene; bootstrap; quality control QC ; quality assurance QA ; quality assessment; empirical Bayes; weighted moderated t-statistic; WAME; DNA microarray;

    Sammanfattning : .... LÄS MER

  5. 4. Weighted Analysis of Microarray Experiments

    Författare :Anders Sjögren; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA microarray; differential expression; gene expression; quality control QC ; quality assurance QA ; quality assessment; generalised linear model; empirical Bayes; weighted moderated statistic; invalid p-value; heteroscedasticity; WAME; heteroscedasticity;

    Sammanfattning : DNA microarrays are strikingly efficient tools for analysing gene expression for large sets of genes simultaneously. The aim is often to identify genes which are differentially expressed between some studied conditions, thereby gaining insight into which cellular mechanisms are differently active between the conditions. LÄS MER

  7. 5. Approaches to differential gene expression analysis in atherosclerosis

    Författare :Tove Andersson; KTH; []
    Nyckelord :representational difference analysis; gene expression profiling; microarray analysis; atherosclerosis; foam cell formation;

    Sammanfattning : Today’s rapid development of powerful tools for geneexpression analysis provides unprecedented resources forelucidating complex molecular events.The objective of this workhas been to apply, combine andevaluate tools for analysis of differential gene expressionusing atherosclerosis as a model system. LÄS MER