Sökning: "reporter gene bioassays"
Hittade 3 avhandlingar innehållade orden reporter gene bioassays.
1. Microplastics in the marine environment and the assessment of potential adverse effects of associated chemicals
Sammanfattning : During the last decade plastics have gained interest by scientists as emerging pollutants particularly in the marine environment due to their ubiquity and persistence. While several studies report the occurrence of microplastics in surface waters globally, there are no harmonized methods to sample and measure microplastics, and the knowledge of toxicological effects in the marine ecosystem is scarce. LÄS MER
2. Human adenoviruses : new bioassays for antiviral screening and CD46 interaction
Sammanfattning : Adenoviruses are common pathogens all over the world. The majority of the population has at some point been infected with an adenovirus. Although severe disease can occur in otherwise healthy individuals an adenovirus infection is most commonly self limited in these cases. LÄS MER
3. Bioassay analysis of dioxin-like compounds : response interactions and environmental transformation of Ah receptor agonists
Sammanfattning : Dioxin-like compounds mediate their toxicity by binding to the aryl hydrocarbon receptor (AhR) and through this receptor a cascade of biochemical and toxic events are triggered. Mechanism-specific dioxin bioassays utilise the AhR coupled induction of endogenous CYP1A proteins or reporter gene systems for detection of dioxin-like compounds and other AhR ligands. LÄS MER
