Sökning: "pulmonary shunt"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden pulmonary shunt.

1. 1. Benefits of Spontaneous Breathing : Compared with Mechanical Ventilation

   Författare :László Vimláti; Michael Lichtwarck-Aschoff; Anders Larsson; Lars Wiklund; Carl-Johan Wickerts; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spontaneous breathing; mechanical ventilation; pulmonary shunt; oxygenation; hypoxic pulmonary vasoconstriction; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

   Sammanfattning : When spontaneous breathing (SB) is allowed during mechanical ventilation (MV), atelectatic lung areas are recruited and oxygenation improves thereby. Whether unsupported SB at its natural pattern (without PEEP and at low pressure/small tidal volume) equally recruits and improves oxygenation, and if so by which mechanism, has not been studied. LÄS MER

3. 2. Synchronized delivery of inspired nitric oxide : Effects on oxygenation and pulmonary tension during artificial ventilation

   Författare :Erkki Heinonen; Tim Higenbottam; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; nitric oxide; pulsed administration; pulmonary hypertension; oxygenation; equine; Cellbiologi; Cell biology; Cellbiologi; Physiology; fysiologi;

   Sammanfattning : Nitric oxide (NO) is a mediator of vascular smooth muscle tension that metabolises rapidly in blood. NO delivered by inhalation can therefore be used as a selective pulmonary vasodilator to relieve pulmonary hypertension or to improve oxygenation with no systemic effects. LÄS MER

4. 3. Endogenous Nitric Oxide Production and Pulmonary Blood Flow : during different experimental lung conditions

   Författare :Manja Nilsson; Filip Fredén; Kristina Hambraeus-Jonzon; Göran Hedenstierna; Eddie Weitzberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nitric oxide; pulmonary blood flow; endotoxin; nitric oxide inhalation; endothelin; hypercapnia; acidosis; lavage-induced lung injury; Anaesthetics and intensive care; Anestesiologi och intensivvård; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

   Sammanfattning : Nitric oxide (NO) is an important regulator of pulmonary blood flow and attenuates hypoxic pulmonary vasoconstriction (HPV). Nitric oxide is synthesized enzymatically in a number of tissues, including the lungs, and can also be generated from reduction of nitrite during hypoxia and acidosis. LÄS MER

5. 4. 3D visualization of vascular lesions and the role of versican in pulmonary arterial hypertension

   Författare :Christian Westöö; Kärlväggsbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pulmonary arterial hypertension; Synchrotron; Imaging; Phase-contrast; Plexiform; Versican;

   Sammanfattning : Pulmonary arterial hypertension (PAH) is a condition that leads to lethal right heart failure. Available treatments provide relief but are far from curative and the vascular remodeling in PAH has been difficult to decipher. LÄS MER

7. 5. Regional pulmonary vasoreactivity, with special reference to nitric oxide, prostacyclin and body posture

   Författare :Danguolé Rimeika; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Regional pulmonary perfusion; nitric oxide; prostacyclin; NOS-inhibition; COX-inhibition; shunt; one-lung ventilation;

   Sammanfattning : The primary aim of the study was to investigate possible mechanisms behind the improved arterial oxygenation in ventilator-treated patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) when turned into prone position. A secondary aim was to discover new knowledge of possible importance for treatment of patients with oxygenation problems in intensive care and during anesthesia. LÄS MER